Feipu Yang

Chinese Academy of Sciences — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index514citations35works2.32yr avg
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Research Topics

Receptor Mechanisms and Signaling(9), Pharmacological Receptor Mechanisms and Effects(9), Neuroscience and Neuropharmacology Research(8), Computational Drug Discovery Methods(5), Neurotransmitter Receptor Influence on Behavior(4)

Publications35 total

Asymmetric Total Synthesis and Anti-Inflammatory Activity of Berbamine, Oxyacanthine, and Related Intermediates
Journal of Natural Products·2025
Design, synthesis, and biological profiling of novel aryl-spirocyclic diamine derivatives with potential antidepressant-like properties
European Journal of Medicinal Chemistry·2025
An Efficient Asymmetric Synthesis of Finerenone via Evans’ Chiral Auxiliary
European Journal of Organic Chemistry·2025· 2 cited
Structural Similarity in Natural Products Leading to Sample Misidentification: A Case Study of the Bisbenzylisoquinoline Alkaloids Oxyacanthine and Berbamine
Journal of Natural Products·2025· 2 cited
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV -2
European Journal of Medicinal Chemistry·2024· 1 cited
Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity
Bioorganic & Medicinal Chemistry Letters·2024· 1 citedOpen Access
Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile
European Journal of Medicinal Chemistry·2024· 6 citedOpen Access
An Alternative Approach to Synthesize Sildenafil via Improved Copper-Catalyzed Cyclization
The Journal of Organic Chemistry·2024· 2 cited
Impurity study of tecovirimat
Heliyon·2024· 2 citedOpen Access
Impurity Study of Tecovirimat
SSRN Electronic Journal·2024Open Access
Improved and ligand-free copper-catalyzed cyclization for an efficient synthesis of benzimidazoles from <i>o</i>-bromoarylamine and nitriles
RSC Advances·2024· 9 citedOpen Access
Glimepiride, a novel soluble epoxide hydrolase inhibitor, protects against heart failure via increasing epoxyeicosatrienoic acids
Journal of Molecular and Cellular Cardiology·2023· 4 cited
An efficient synthesis of the last step key intermediate for telmisartan via Pd-catalyzed carbonylative cyclization
Tetrahedron·2023· 2 cited
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
Nature Communications·2023· 95 citedOpen Access
Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene
Organic Process Research & Development·2023· 6 cited
An Efficient Synthesis of the Last Step Key Intermediate for Telmisartan Via Pd Catalyzed Carbonylative Cyclization
SSRN Electronic Journal·2023Open Access
Pharmacokinetics, mass balance, and metabolism of [14C]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension
Acta Pharmacologica Sinica·2022· 15 citedOpen Access
Facile and Cost-Effective Route for the Synthesis of Simmerafil
Organic Process Research & Development·2021· 1 cited
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
Cell Research·2021· 185 citedOpen Access
TPN672: A Novel Serotonin-Dopamine Receptor Modulator for the Treatment of Schizophrenia
Journal of Pharmacology and Experimental Therapeutics·2021· 7 citedOpen Access
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Frequent Co-authors

Jingshan Shen(35), Xiangrui Jiang(19), He Yang(13), Chunhui Wu(12), Abdullajon Odilov(11), Emmanuel Mintah Bonku(9), Hongjian Qin(9), Guanghui Tian(8), Tianwen Hu(8), Hualiang Jiang(7), Qingjie Zhao(7), Zhen Wang(7), Fuqiang Zhu(7), Samuel Desta Guma(6), Yuanchao Xie(5), Mingshuo Xu(5), Haji Akber Aisa(5), Safomuddin Abduahadi(5), Leike Zhang(4), Yongjian Liu(4)