Lei Xie

The Graduate Center, CUNY — United States

Computer Science · Physical Sciences

54h-index9.9kcitations329works4.22yr avg
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Research Topics

Computational Drug Discovery Methods(90), Speech Recognition and Synthesis(55), Bioinformatics and Genomic Networks(51), Speech and Audio Processing(42), Music and Audio Processing(30)

Publications328 total

Multimodal out-of-distribution individual uncertainty quantification enhances binding affinity prediction for polypharmacology
Nature Machine Intelligence·2025Open Access
Integrating explainable artificial intelligence with multiomics systems biology and electronic health record data mining for personalized drug repurposing in Alzheimer’s disease
Briefings in Bioinformatics·2025Open Access
Discovery of a selective α2C-AR scaffold from a molecular hybridization approach
Bioorganic & Medicinal Chemistry·2025
Towards Building Speech Large Language Models for Multitask Understanding in Low-Resource Languages
arXiv (Cornell University)·2025Open Access
MPO: Multidimensional Preference Optimization for Language Model-based Text-to-Speech
arXiv (Cornell University)·2025Open Access
EASY: Emotion-aware Speaker Anonymization via Factorized Distillation
2025· 1 cited
Selective Invocation for Multilingual ASR: A Cost-effective Approach Adapting to Speech Recognition Difficulty
2025
AISHELL-5: The First Open-Source In-Car Multi-Channel Multi-Speaker Speech Dataset for Automatic Speech Diarization and Recognition
2025
Cross-level Cross-Scale Inference and Imputation of Single-cell Spatial Proteomics
2025Open Access
ContextASR-Bench: A Massive Contextual Speech Recognition Benchmark
arXiv (Cornell University)·2025Open Access
DEM-LES study on mixing and segregation characteristics for binary-sized particles in a liquid-solid fluidized bed
Powder Technology·2025
Contextualized Automatic Speech Recognition with Dynamic Vocabulary Prediction and Activation
arXiv (Cornell University)·2025Open Access
Delayed-KD: Delayed Knowledge Distillation based CTC for Low-Latency Streaming ASR
arXiv (Cornell University)·2025Open Access
Selective Invocation for Multilingual ASR: A Cost-effective Approach Adapting to Speech Recognition Difficulty
arXiv (Cornell University)·2025Open Access
Automated Fault Detection and Diagnosis for Large-Scale Cloud Systems Based on Log Analysis
2025
Phosphine-catalyzed [3 + 2]-annulation of Morita–Baylis–Hillman carbonates with benzofuran-derived azadienes: Synthesis of spiro-cyclopentane benzofurans
Tetrahedron·2025· 1 cited
FlexSpeech: Towards Stable, Controllable and Expressive Text-to-Speech
arXiv (Cornell University)·2025Open Access
NNKcat: deep neural network to predict catalytic constants (Kcat) by integrating protein sequence and substrate structure with enhanced data imbalance handling
Briefings in Bioinformatics·2025· 2 citedOpen Access
Reinforcement Learning-Driven Plant-Wide Refinery Planning Using Model Decomposition
arXiv (Cornell University)·2025Open Access
AI‐Driven Applications in Clinical Pharmacology and Translational Science: Insights From the ASCPT 2024 AI Preconference
Clinical and Translational Science·2025· 10 citedOpen Access
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Frequent Co-authors

Philip E. Bourne(19), Li Xie(9), Xingguo Li(7), Sarah Kinnings(5), Jie Zheng(5), Hu Zhou(3), Yue Qiu(3), Rong Yang(3), Jianglan Qu(3), Hansaim Lim(3), Di He(3), Nina Liu(2), Peter J. Tonge(2), Fuquan Jiang(2), Richard M. Jackson(2), Yan Li(2), Yaoqi Li(2), Aleksandar Poleksić(2), Yinliang Zhang(2), Hua Wu(2)