Laura Denby

The Queen's Medical Research Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index4.2kcitations119works2.22yr avg
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Research Topics

MicroRNA in disease regulation(23), Virus-based gene therapy research(20), Renal and related cancers(17), Chronic Kidney Disease and Diabetes(15), Cancer-related molecular mechanisms research(13)

Publications106 total

P30  Evaluating the potential of cis- and trans-4-[ <sup>18</sup> F]fluoro-L-proline positron emission tomography as biomarkers of active collagen biosynthesis in cardiometabolic diseases
Poster·2025Open Access
Low circulating miR-190a-5p predicts progression of chronic kidney disease
Nature Communications·2025Open Access
AntimiR uptake by human proximal tubule epithelial cells is predominantly by macropinocytosis
Scientific Reports·2025Open Access
Multiomic analysis of human kidney disease identifies a tractable inflammatory and pro-fibrotic tubular cell phenotype
Nature Communications·2025· 12 citedOpen Access
Urinary Clusterin is a Biomarker of Renal Epithelial Senescence and Predicts Human Kidney Disease Progression
Kidney International Reports·2025· 3 citedOpen Access
Resident T Cells and Intrarenal Inflammation
Journal of the American Society of Nephrology·2025· 1 cited
#2069 Elucidating the function of novel Arg1+/Clec4d+ scar-associated monocyte-derived macrophage population in driving fibrosis in kidney disease models
Nephrology Dialysis Transplantation·2024Open Access
P2X7 receptor knockout does not alter renal function or prevent angiotensin II-induced kidney injury in F344 rats
Physiology·2024
#2607 Generation of a tissue resident macrophage depleted reporter rat to examine cardiovascular homeostasis and kidney disease
Nephrology Dialysis Transplantation·2024Open Access
#2605 Evaluation of cardiac fetal gene program in experimental uremia
Nephrology Dialysis Transplantation·2024Open Access
P2X7 receptor knockout does not alter renal function or prevent angiotensin II-induced kidney injury in F344 rats
Scientific Reports·2024· 5 citedOpen Access
Low circulating miR-190a-5p predicts progression of chronic kidney disease.
2024Open Access
Low circulating miR-190a-5p predicts progression of chronic kidney disease.
2024Open Access
Urinary Clusterin is a biomarker of renal epithelial senescence and predicts human kidney disease progression
2024· 1 citedOpen Access
Multiomic analysis of human kidney disease identifies a tractable inflammatory, pro-fibrotic tubular cell phenotype
2024· 2 citedOpen Access
Beta Blockade Prevents Cardiac Morphological and Molecular Remodelling in Experimental Uremia
International Journal of Molecular Sciences·2023· 3 citedOpen Access
Mapping cardiac remodeling in chronic kidney disease
Science Advances·2023· 17 citedOpen Access
Elucidating the Function of a Novel Arg-1+/Clec4d+ Scar-Associated Monocyte-Derived Macrophage Population in Driving Fibrosis in Kidney Disease Models
Journal of the American Society of Nephrology·2023
Characterising Human Kidney Disease Using Single-Cell Resolution Spatial Transcriptomics
Journal of the American Society of Nephrology·2023
Induced Senescent Cells Recruit Leukocytes and Permit Their Own Clearance from Healthy Young Kidneys
Journal of the American Society of Nephrology·2023
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Frequent Co-authors

Andrew H. Baker(28), Stuart A. Nicklin(12), Bryan R. Conway(12), Neil C. Henderson(9), Jeremy Hughes(9), Carolynn Cairns(8), Lorraine M. Work(8), Eoin O’Sullivan(6), David A. Ferenbach(6), Tamir Chandra(6), John H. McVey(5), Oliver Teenan(5), C Bénézech(5), Julie Rodor(5), Jenny A. Greig(4), John McClure(4), James O’Sullivan(4), Katie Connor(4), Kevin Stewart(4), Katie J. Mylonas(4)