Simona Pace

University of Salerno — Italy

Medicine · Health Sciences

28h-index2.2kcitations84works3.02yr avg
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Research Topics

Inflammatory mediators and NSAID effects(23), Asthma and respiratory diseases(15), Eicosanoids and Hypertension Pharmacology(12), Immune Response and Inflammation(10), Immune cells in cancer(8)

Publications84 total

Sex‐related susceptibility to pulmonary fibrosis development in mice
British Journal of Pharmacology·2026Open Access
Evaluation of molecular mechanisms of (Z)-3-(pentadec-10′-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis
Redox Biology·2025Open Access
Uncovering anti-inflammatory natural products that synergize with supplemented omega-3 PUFA for eliciting endogenous inflammation resolution signals
Biomedicine & Pharmacotherapy·2025· 2 citedOpen Access
A Comprehensive <i>In Vitro</i> Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors
Journal of Medicinal Chemistry·2024· 3 citedOpen Access
Sex hormone deprivation abolishes sex‐specific differences in murine colon inflammation and related lipid mediator production
The FASEB Journal·2024· 10 citedOpen Access
Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators
Cell chemical biology·2023· 25 citedOpen Access
Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution
Proceedings of the National Academy of Sciences·2023· 26 citedOpen Access
Allosteric Activation of 15‐Lipoxygenase‐1 by Boswellic Acid Induces the Lipid Mediator Class Switch to Promote Resolution of Inflammation
Advanced Science·2022· 28 citedOpen Access
Highly potent and selective 5-lipoxygenase inhibition by new, simple heteroaryl-substituted catechols for treatment of inflammation
Biochemical Pharmacology·2022· 8 cited
Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E<sub>2</sub> and Leukotriene Biosynthesis Inhibitors
ACS Medicinal Chemistry Letters·2022· 3 citedOpen Access
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: <i>In Vitro</i> and <i>In Vivo</i> Anti-Inflammatory Characterization
Journal of Medicinal Chemistry·2022· 29 citedOpen Access
Modulation of Inflammation-Related Lipid Mediator Pathways by Celastrol During Human Macrophage Polarization
Journal of Inflammation Research·2022· 7 citedOpen Access
Mycobacterium tuberculosis-Induced Upregulation of the COX-2/mPGES-1 Pathway in Human Macrophages Is Abrogated by Sulfasalazine
Frontiers in Immunology·2022· 18 citedOpen Access
<i>Staphylococcus aureus</i> controls eicosanoid and specialized pro‐resolving mediator production via lipoteichoic acid
Immunology·2022· 15 citedOpen Access
Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis
Frontiers in Pharmacology·2022· 12 citedOpen Access
Switching from inflammation to resolution: what can we learn from medicinal plants?
Planta Medica·2021
The α-tocopherol-derived long-chain metabolite α-13′-COOH mediates endotoxin tolerance and modulates the inflammatory response via MAPK and NFκB pathways
Free Radical Biology and Medicine·2021· 13 citedOpen Access
Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation
Journal of Medicinal Chemistry·2021· 16 citedOpen Access
Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides
Biomolecules·2021· 16 citedOpen Access
From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution
Acta Pharmaceutica Sinica B·2021· 15 citedOpen Access
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Frequent Co-authors

Oliver Werz(45), Antonietta Rossi(27), Jana Gerstmeier(16), Lidia Sautebin(14), Andreas Koeberle(13), Paul M. Jordan(11), Fabiana Troisi(11), Christina Weinigel(11), Rossella Bilancia(11), Silke Rummler(9), Fiorentina Roviezzo(8), Markus Werner(7), Ulrike Garscha(6), Veronika Temml(6), Friedemann Börner(6), Zhigang Rao(5), Christian Kretzer(5), Charles N. Serhan(5), Stefanie König(5), Hermann Stuppner(5)