Ineke Brouwer

The Netherlands Cancer Institute — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index837citations31works0.02yr avg
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Research Topics

Genomics and Chromatin Dynamics(11), DNA and Nucleic Acid Chemistry(10), DNA Repair Mechanisms(8), Gene Regulatory Network Analysis(6), RNA Research and Splicing(5)

Publications31 total

Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly
Molecular Cell·2023· 6 citedOpen Access
Measuring Transcription Dynamics of Individual Genes Inside Living Cells
Methods in molecular biology·2023· 2 citedOpen Access
Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting
Nature Structural & Molecular Biology·2023· 38 citedOpen Access
DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes
Molecular Cell·2023· 56 citedOpen Access
A chromatin-associated regulator of RNA Polymerase III assembly at tRNA genes revealed by locus-specific proteomics
2023Open Access
Transcription factor clusters enable target search but do not contribute to target gene activation
Nucleic Acids Research·2023· 48 citedOpen Access
Transcription factor clusters enable target search but do not contribute to target gene activation
2022· 5 citedOpen Access
DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes
2022· 10 citedOpen Access
Transcription-replication coordination revealed in single live cells
Nucleic Acids Research·2022· 33 citedOpen Access
Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting
2021· 2 citedOpen Access
Pulmonary valve tissue engineering strategies in large animal models
PLoS ONE·2021· 9 citedOpen Access
Optimized protocol for single-molecule RNA FISH to visualize gene expression in S. cerevisiae
STAR Protocols·2021· 15 citedOpen Access
Single-Molecule Fluorescence Imaging in Living Saccharomyces cerevisiae Cells
STAR Protocols·2020· 29 citedOpen Access
Imaging unlabeled proteins on DNA with super-resolution
Nucleic Acids Research·2020· 23 citedOpen Access
Visualizing transcription: key to understanding gene expression dynamics
Current Opinion in Chemical Biology·2019· 80 citedOpen Access
Two distinct conformational states define the interaction of human <scp>RAD</scp> 51‐ <scp>ATP</scp> with single‐stranded <scp>DNA</scp>
The EMBO Journal·2018· 87 citedOpen Access
Erratum: Corrigendum: Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA
Nature·2017· 4 citedOpen Access
Human RAD52 Captures and Holds DNA Strands, Increases DNA Flexibility, and Prevents Melting of Duplex DNA: Implications for DNA Recombination
Cell Reports·2017· 36 citedOpen Access
Probing DNA–DNA Interactions with a Combination of Quadruple-Trap Optical Tweezers and Microfluidics
Methods in molecular biology·2016· 10 cited
Versatile Quadruple-Trap Optical Tweezers for Dual DNA Experiments
Methods in molecular biology·2016· 13 cited
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Frequent Co-authors

Gijs J. L. Wuite(16), Tineke L. Lenstra(13), Erwin J.G. Peterman(12), Andrea Candelli(9), Mauro Modesti(9), Gerrit Sitters(6), Iddo Heller(6), Heta Patel(6), Wim Pomp(5), Niels Laurens(5), Stephanie J. Heerema(4), Fred van Leeuwen(4), Hongshan Zhang(3), Davide Normanno(3), Joseph V.W. Meeussen(3), Asiya Giniatullina(3), Alexander J. Groffen(3), Andreas S. Biebricher(3), Abinadabe J. Melo de(2), Stéphanie Bernard(2)