Stephen J. Headey

Australian Regenerative Medicine Institute — Australia

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index1.3kcitations70works0.02yr avg
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Research Topics

Metabolism, Diabetes, and Cancer(10), HIV Research and Treatment(9), HIV/AIDS drug development and treatment(9), Growth Hormone and Insulin-like Growth Factors(8), Bacterial Genetics and Biotechnology(7)

Publications70 total

Exploring the Ligandability of 53BP1 through Fragment-Based Approaches
ACS Medicinal Chemistry Letters·2025Open Access
Exploring the Ligandability of 53BP1 Through Fragment-Based Approaches
2024Open Access
Improved gene targeting in vivo using EoHR, a small molecule inhibitor of 53BP1
2024Open Access
Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain
Journal of Medicinal Chemistry·2023· 8 citedOpen Access
Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach
Molecules·2023· 7 citedOpen Access
Enhanced homology-directed repair for highly efficient gene editing in hematopoietic stem/progenitor cells
Blood·2021· 72 citedOpen Access
Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra Terminal Domain
2020Open Access
Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra Terminal Domain
2020Open Access
Tudor Domain of Tumor suppressor p53BP1 with MFP-4184
2019
Tudor Domain of Tumor suppressor p53BP1 with MFP-2706
2019
Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis
Cell Reports·2019· 38 citedOpen Access
A ligand-induced structural change in fatty acid–binding protein 1 is associated with potentiation of peroxisome proliferator–activated receptor α agonists
Journal of Biological Chemistry·2019· 31 citedOpen Access
Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import
Cellular Microbiology·2018· 26 citedOpen Access
Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens
Journal of Biological Chemistry·2018· 14 citedOpen Access
Structural basis for the inhibition of poxvirus assembly by the antibiotic rifampicin
Proceedings of the National Academy of Sciences·2018· 56 citedOpen Access
Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV‐1 Integrase
ChemMedChem·2018· 7 citedOpen Access
Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction
Antibiotics·2018· 18 citedOpen Access
Δ‐Myrtoxin‐Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane‐Disrupting, and Nociceptive Activities
Angewandte Chemie International Edition·2017· 34 citedOpen Access
Δ‐Myrtoxin‐Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane‐Disrupting, and Nociceptive Activities
Angewandte Chemie·2017· 1 cited
Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1
PLoS ONE·2017· 21 citedOpen Access
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Frequent Co-authors

M.J. Scanlon(29), Biswaranjan Mohanty(11), Jamie S. Simpson(9), David K. Chalmers(7), B.C. Doak(7), Leon A. Bach(6), Raymond S. Norton(6), M.L. Williams(6), J. Wielens(5), Kieran Rimmer(5), Menachem J. Gunzburg(5), Michael W. Parker(4), Luke A. Adams(4), O.V. Ilyichova(4), Mark D. Mulcair(4), Stephen R. Shouldice(4), Mansha Vazirani(4), Jennifer L. Martin(4), Begoña Heras(4), Matthew C. J. Wilce(4)