Chen-Pin Hung

Bristol-Myers Squibb (United States) — United States

Medicine · Health Sciences

7h-index192citations9works0.02yr avg
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Research Topics

Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis(2), PI3K/AKT/mTOR signaling in cancer(2), Receptor Mechanisms and Signaling(2), Sphingolipid Metabolism and Signaling(2), Crystallization and Solubility Studies(2)

Publications9 total

Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA<sub>1</sub>) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases
Journal of Medicinal Chemistry·2021· 53 citedOpen Access
LPA1 antagonist BMS-986278 for idiopathic pulmonary fibrosis: Preclinical pharmacological in vitro and in vivo evaluation
2019· 11 cited
Discovery of 5-Chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1<i>H</i>)-one (BMS-903452), an Antidiabetic Clinical Candidate Targeting GPR119
Journal of Medicinal Chemistry·2014· 45 citedOpen Access
Synthesis and SAR of potent and selective tetrahydropyrazinoisoquinolinone 5-HT2C receptor agonists
Bioorganic & Medicinal Chemistry Letters·2013· 15 citedOpen Access
CCDC 897809: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
Synthesis and SAR of 2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-c]isoquinolin-5(9bH)-ones as 5-HT2C receptor agonists
Bioorganic & Medicinal Chemistry Letters·2012· 15 citedOpen Access
Tricyclic dihydroquinazolinones as novel 5-HT2C selective and orally efficacious anti-obesity agents
Bioorganic & Medicinal Chemistry Letters·2009· 20 citedOpen Access
CCDC 632659: Experimental Crystal Structure Determination
The Cambridge Structural Database·2008Open Access
Discovery of ( <i>R</i> )-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1- <i>a</i> ]isoindol- 6(2 <i>H</i> )-one, a Selective, Orally Active Agonist of the 5-HT <sub>2C</sub> Receptor
Journal of Medicinal Chemistry·2007· 33 citedOpen Access

Frequent Co-authors

Jeffrey A. Robl(8), Sarah E. Malmstrom(7), Ginger Wu(6), Thao Ung(6), William J. Keim(6), Mary Jane Cullen(6), Kenneth W. Rohrbach(6), Qinling Qu(6), Mary Ann Pelleymounter(6), Karen A. Rossi(5), Keith J. Miller(5), Jinping Gan(4), Bradley A. Zinker(3), Stephanie Boehm(3), Dean A. Wacker(3), Xueying Cao(3), James J. Devenny(3), Robert F. Kaltenbach(2), Jun Shi(2), Shiwei Tao(2)