Ben Tseng

Chemistry · Physical Sciences

47h-index6.7kcitations104works0.02yr avg
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Research Topics

Synthesis and biological activity(27), Synthesis and Characterization of Heterocyclic Compounds(18), DNA Repair Mechanisms(14), Cell death mechanisms and regulation(12), Synthesis of Organic Compounds(11)

Publications104 total

Supplementary Figure S1 from The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach
2023Open Access
Data from The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach
2023Open Access
Supplementary Figure S1 from The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach
2023Open Access
Data from The discovery and mechanism of action of novel tumor-selective and apoptosis-inducing 3,5-diaryl-1,2,4-oxadiazole series using a chemical genetics approach
2023Open Access
White matter integrity in physically fit older adults
NeuroImage·2013· 149 citedOpen Access
Caspase Inhibitor Therapy Synergizes With Costimulation Blockade to Promote Indefinite Islet Allograft Survival
Diabetes·2010· 21 citedOpen Access
Discovery of N-methyl-4-(4-methoxyanilino)quinazolines as potent apoptosis inducers. Structure–activity relationship of the quinazoline ring
Bioorganic & Medicinal Chemistry Letters·2010· 49 cited
Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure–activity relationships of the 9-oxo-9H-fluorene ring
Bioorganic & Medicinal Chemistry Letters·2009· 23 cited
ChemInform Abstract: Discovery of 3‐Aryl‐5‐aryl‐1,2,4‐oxadiazoles as a New Series of Apoptosis Inducers. Part 2. Identification of More Aqueous Soluble Analogues as Potential Anticancer Agents.
ChemInform·2009
Pharmacokinetic and pharmacodynamic results of a 4-hr IV administration phase I study with EPC2407, a novel vascular disrupting agent
Journal of Clinical Oncology·2009· 6 cited
Discovery of 3-aryl-5-aryl-1,2,4-oxadiazoles as a new series of apoptosis inducers. 2. Identification of more aqueous soluble analogs as potential anticancer agents
Bioorganic & Medicinal Chemistry Letters·2009· 47 cited
Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure–activity relationships of the 4-, 5-, 6-, 7- and 8-positions
Bioorganic & Medicinal Chemistry Letters·2009· 41 cited
Discovery of 4-anilino-N-methylthieno[3,2-d]pyrimidines and 4-anilino-N-methylthieno[2,3-d]pyrimidines as potent apoptosis inducers
Bioorganic & Medicinal Chemistry Letters·2009· 41 cited
Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure–activity relationships of the carboxamide group
Bioorganic & Medicinal Chemistry Letters·2009· 18 cited
Discovery of substituted N′-(2-oxoindolin-3-ylidene)benzohydrazides as new apoptosis inducers using a cell- and caspase-based HTS assay
Bioorganic & Medicinal Chemistry Letters·2009· 37 citedOpen Access
Discovery of <i>N</i>-(4-Methoxyphenyl)-<i>N</i>,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration
Journal of Medicinal Chemistry·2009· 121 cited
Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure–activity relationships of the 2-aryl group
Bioorganic & Medicinal Chemistry Letters·2009· 14 cited
Discovery and structure–activity relationships of (2-(arylthio)benzylideneamino)guanidines as a novel series of potent apoptosis inducers
Bioorganic & Medicinal Chemistry·2009· 13 cited
Erratum to “Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay” [Bioorg. Med. Chem. Lett. 18 (2008) 5571–5575]
Bioorganic & Medicinal Chemistry Letters·2008· 2 cited
Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2(1H)-quinolinones through a Myc-dependent pathway
Cancer Letters·2008· 74 cited
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Frequent Co-authors

Sui Xiong Cai(27), Shailaja Kasibhatla(26), John Drewe(26), William Kemnitzer(12), Songchun Jiang(12), Mehran Goulian(10), Candace Crogan‐Grundy(9), Nilantha Sirisoma(9), Henriette Gourdeau(8), Han‐Zhong Zhang(8), Serge Lamothe(7), Réal Denis(6), Giorgio Attardo(5), Jared Kuemmerle(5), Azra Pervin(5), John Herich(4), John Guastella(4), Ling Qiu(4), Christopher M. Pleiman(4), Denis Labrecque(3)