Megan E. Fung

Brigham and Women's Hospital — United States

Medicine · Health Sciences

6h-index315citations56works7.12yr avg
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Research Topics

Cancer Immunotherapy and Biomarkers(45), Immune Cell Function and Interaction(24), CAR-T cell therapy research(21), Immune cells in cancer(12), Single-cell and spatial transcriptomics(5)

Publications56 total

PD-1 regulates tumor-infiltrating CD8+ T cells in both a cell-intrinsic and a cell-extrinsic fashion
The Journal of Experimental Medicine·2025· 5 citedOpen Access
Abstract LB066: Cytokine and chemokine screening reveals altered NK-DC-T cell crosstalk in the aged tumor microenvironment
Cancer Research·2025
Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control
UNC Libraries·2025Open Access
Figure S2 from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
Figure S8 from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
Figure S6 from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
Figure S7 from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
Figure S3 from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
Figure S4 from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
Figure S5 from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
Figure S1 from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
Data from Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
2024Open Access
564 Loss of PD-1 can improve the functionality of anti-tumor CD8 T cells through both direct cell-intrinsic and indirect cell-extrinsic mechanisms
Regular and Young Investigator Award Abstracts·2024Open Access
Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control
Nature Immunology·2024· 27 citedOpen Access
Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
Cancer Immunology Research·2024· 14 citedOpen Access
The aged tumor microenvironment limits T cell control of cancer
Nature Immunology·2024· 75 citedOpen Access
Abstract 3921: The aged tumor microenvironment limits CD8+ T cell control of cancer
Cancer Research·2024
Supplementary Figure 6 from Formate Supplementation Enhances Antitumor CD8<sup>+</sup> T-cell Fitness and Efficacy of PD-1 Blockade
2023Open Access
Supplementary Figure 15 from Formate Supplementation Enhances Antitumor CD8<sup>+</sup> T-cell Fitness and Efficacy of PD-1 Blockade
2023Open Access
Supplementary Figure 5 from Formate Supplementation Enhances Antitumor CD8<sup>+</sup> T-cell Fitness and Efficacy of PD-1 Blockade
2023Open Access
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Frequent Co-authors

Arlene H. Sharpe(46), Jared H. Rowe(41), Gordon J. Freeman(39), Marcia C. Haigis(39), Shakchhi Joshi(37), Joon Seok Park(37), Osmaan Shahid(35), Kristen E. Pauken(33), Natalia E. Sifnugel(31), Martin W. LaFleur(31), Ilaria Elia(29), Emily F. Gaudiano(29), Sheila Johnson(29), Amy G. Reynolds(29), Joshua D. Rabinowitz(29), Thao H. Nguyen(11), Thomas S. Conway(11), Amy Y. Huang(10), Brian C. Miller(10), Alison E. Ringel(10)