Diane E. Milenic

Medicine · Health Sciences

50h-index7.1kcitations128works0.02yr avg
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Research Topics

Radiopharmaceutical Chemistry and Applications(93), Monoclonal and Polyclonal Antibodies Research(65), Medical Imaging Techniques and Applications(18), HER2/EGFR in Cancer Research(16), Glycosylation and Glycoproteins Research(14)

Publications128 total

Exploration of a F(ab′) <sub>2</sub> Fragment as the Targeting Agent of α-Radiation Therapy: A Comparison of the Therapeutic Benefit of Intraperitoneal and Intravenous Administered Radioimmunotherapy
Cancer Biotherapy and Radiopharmaceuticals·2018· 12 citedOpen Access
Targeted α-Particle Radiation Therapy of HER1-Positive Disseminated Intraperitoneal Disease: An Investigation of the Human Anti-EGFR Monoclonal Antibody, Panitumumab
Translational Oncology·2017· 24 citedOpen Access
Comparative studies on the therapeutic benefit of targeted α-particle radiation therapy for the treatment of disseminated intraperitoneal disease
Dalton Transactions·2017· 7 citedOpen Access
Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and 212Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model
PLoS ONE·2016· 14 citedOpen Access
Mechanisms of Cell Killing Response from Low Linear Energy Transfer (LET) Radiation Originating from 177Lu Radioimmunotherapy Targeting Disseminated Intraperitoneal Tumor Xenografts
International Journal of Molecular Sciences·2016· 34 citedOpen Access
Bench to Bedside: Stability Studies of GMP Produced Trastuzumab-TCMC in Support of a Clinical Trial
Pharmaceuticals·2015· 18 citedOpen Access
Toxicological Studies of 212Pb Intravenously or Intraperitoneally Injected into Mice for a Phase 1 Trial
Pharmaceuticals·2015· 25 citedOpen Access
Synthesis and characterization of gadolinium—Peptidomimetic complex as an αvβ3 integrin targeted MR contrast agent
Bioorganic & Medicinal Chemistry Letters·2015· 7 citedOpen Access
Evaluation of cetuximab as a candidate for targeted α-particle radiation therapy of HER1-positive disseminated intraperitoneal disease
mAbs·2015· 40 citedOpen Access
Abstract 4290: <i>In vitro</i> &amp; <i>in vivo</i> analysis of indocyanine green-labeled panitumumab for optical imaging: a cautionary tale
Cancer Research·2014
Abstract 1770: Viral-based nanoparticles: a new therapeutic approach for anticancer therapy
Cancer Research·2014
Impact of α-Targeted Radiation Therapy on Gene Expression in a Pre-Clinical Model for Disseminated Peritoneal Disease when Combined with Paclitaxel
PLoS ONE·2014· 14 citedOpen Access
<i>In Vitro</i> and <i>In Vivo</i> Analysis of Indocyanine Green-Labeled Panitumumab for Optical Imaging—A Cautionary Tale
Bioconjugate Chemistry·2014· 35 citedOpen Access
Gene expression profiling upon <sup>212</sup>Pb‐<scp>TCMC</scp>‐trastuzumab treatment in the <scp>LS</scp>‐174T i.p. xenograft model
Cancer Medicine·2013· 26 citedOpen Access
Evaluation of Platinum Chemotherapy in Combination with HER2-Targeted α-Particle Radiation
Cancer Biotherapy and Radiopharmaceuticals·2013· 24 citedOpen Access
212Pb-radioimmunotherapy potentiates paclitaxel-induced cell killing efficacy by perturbing the mitotic spindle checkpoint
British Journal of Cancer·2013· 26 citedOpen Access
Methodology for labeling proteins and peptides with lead-212 (212Pb)
Nuclear Medicine and Biology·2013· 70 cited
Abstract 1601: Paclitaxel potentiates212Pb-radioimmunotherapy-induced cell killing efficacy by perturbing mitotic spindle checkpoint.
Cancer Research·2013· 1 cited
Abstract 718: Optical molecular imaging of HER1-positive cancer using near-infrared PEGylated indocyanine green-labeled panitumumab.
Cancer Research·2013
Preclinical evaluation of NETA-based bifunctional ligand for radioimmunotherapy applications using 212Bi and 213Bi: Radiolabeling, serum stability, and biodistribution and tumor uptake studies
Nuclear Medicine and Biology·2013· 51 citedOpen Access
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Frequent Co-authors

Martin W. Brechbiel(32), Kayhan Garmestani(17), Kwamena E. Baidoo(13), Jeffrey Schlom(10), David Colcher(8), Tapan K. Nayak(7), Erik D. Brady(6), Karen Wong(6), Dangshe Ma(6), Takashi Yokota(5), Jeffrey Schlom(5), Mario Roselli(5), Marc Whitlow(4), James F. Wood(4), Celeste A.S. Regino(4), Paul S. Albert(4), Alia Abdulla(4), S. V. S. Kashmiri(4), Hyun‐Soon Chong(4), Lara L. Chappell(3)