Juan Iovanna

Centre National de la Recherche Scientifique — France

Medicine · Health Sciences

85h-index36.4kcitations706works8.02yr avg
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Research Topics

Pancreatic and Hepatic Oncology Research(226), Pancreatitis Pathology and Treatment(97), Cancer Genomics and Diagnostics(82), Epigenetics and DNA Methylation(76), Endoplasmic Reticulum Stress and Disease(66)

Publications700 total

Why isn’t an oncogenic mutation in KRAS enough to induce and sustain transformation?
Critical Reviews in Oncology/Hematology·2026
Adaptation of redox metabolism in drug-tolerant persister cells is a vulnerability to prevent relapse in pancreatic cancer
Oncogenesis·2025Open Access
Corrigendum to “Bimodal silencing of the acinar cell-specific mRNA translation repressor PAIP2B defines a poor prognostic subgroup within the classical pancreatic tumor type” [Cancer Lett. 632 (2025) 217971]
Cancer Letters·2025Open Access
Evaluating the therapeutic role of salvianolic acid A on pancreatic cancer cells through interaction with the intrinsically disordered protein NUPR1
International Journal of Biological Macromolecules·2025Open Access
Synergistic antitumor activity of sorafenib and the NUPR1 inhibitor LZX-2-73 in multiple cancer models
Cell Death and Disease·2025Open Access
PANCprofiler: a transcriptomic tool for intratumoral cell stratification unraveling treatment-resistant phenotypes in pancreatic ductal adenocarcinoma
Pancreatology·2025
NUPR1-dependent Stress Granules are present in Caerulein-induced chronic pancreatitis models
Pancreatology·2025
Toward Precision Chemotherapy for Pancreatic Cancer Guided by Transcriptomic Signatures
United European Gastroenterology Journal·2025· 1 citedOpen Access
Correction to “Novel Triazole Ribonucleoside Down-Regulates Heat Shock Protein 27 and Induces Potent Anticancer Activity on Drug-Resistant Pancreatic Cancer”
Journal of Medicinal Chemistry·2025
Correction to “Discovery of Novel Arylethynyltriazole Ribonucleosides with Selective and Effective Antiviral and Antiproliferative Activity”
Journal of Medicinal Chemistry·2025
The mitochondrial catastrophe induced by NUPR1 inhibitors as a novel strategy to fight against cancer
Critical Reviews in Oncology/Hematology·2025
Bimodal silencing of the acinar cell-specific mRNA translation repressor PAIP2B defines a poor prognostic subgroup within the classical pancreatic tumor type
Cancer Letters·2025
Correction: Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E
Oncogene·2025Open Access
Mechanisms of induced resistance to the antitumoral agent ZZW-115 in pancreas ductal adenocarcinoma
Scientific Reports·2025· 2 citedOpen Access
Understanding the heterogeneity of pancreatic ductal adenocarcinoma
Translational Oncology·2025· 3 citedOpen Access
The intrinsically disordered protein <scp>NUPR1</scp> binds to phospholipids
Protein Science·2025· 2 citedOpen Access
Self-assembling dendrimer nanodrug formulations for decreased hERG-related toxicity and enhanced therapeutic efficacy
Science Advances·2025· 6 citedOpen Access
Organosilicon molecules bind to the intrinsically disordered protein NUPR1 by clamping its hot-spots
Archives of Biochemistry and Biophysics·2025· 1 citedOpen Access
Oncogenic stress response mechanisms as new therapeutic targets in cancer treatment: A review
Medicine·2025Open Access
Medical management of pancreatic cancer: from personalization to broadening treatment strategies
Cancer Treatment Reviews·2025· 8 citedOpen Access
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Frequent Co-authors

Nelson Dusetti(18), Sophie Vasseur(14), Stéphane Garcia(11), Richard Tomasini(9), Jean–Charles Dagorn(8), Alice Carrier(6), Odile Gayet(6), Jonathan A. Nowak(5), Julie Roques(5), Gustavo V. Mallo(5), Guillermo Velasco(4), Rémy Nicolle(4), Mylène Seux(4), Marie‐Josèphe Pébusque(4), Fabienne Guillaumond(4), Sophie Lac(4), Céline Loncle(4), Marie‐Noëlle Lavaut(4), Olivıer Turrini(4), Véronique Secq(4)