Mario F. Fraga

Universidad de Oviedo — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

93h-index40.1kcitations492works2.82yr avg
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Research Topics

Epigenetics and DNA Methylation(272), RNA modifications and cancer(87), Cancer-related gene regulation(63), Genomics and Chromatin Dynamics(35), Cancer, Hypoxia, and Metabolism(32)

Publications491 total

Integrated miRNA–mRNA Analysis Reveals Dysregulated Regulatory Networks in Visceral Adipose Tissue Linked to Obesity and Type 2 Diabetes
2026Open Access
Epigenetic and metabolic rewiring in metastatic pheochromocytomas and paragangliomas driven by SDHB mutations
Communications Biology·2026Open Access
The miR-200 family in the context of obesity and type 2 diabetes
Diabetes Research and Clinical Practice·2025· 1 citedOpen Access
Age-dependent effect of environmental enrichment on the neural 3D chromatin interactome
Cell Reports·2025Open Access
HDAC7 induction combined with standard-of-care chemotherapy provides a therapeutic advantage in t(4;11) infant B-cell acute lymphoblastic leukemia
Biomarker Research·2025Open Access
Targeting osteoarthritis with small extracellular vesicle therapy: potential and perspectives
Frontiers in Bioengineering and Biotechnology·2025· 4 citedOpen Access
Data from Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
2025Open Access
Supplementary Tables S1-S16 from Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
2025Open Access
Supplementary Tables S1-S16 from Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
2025Open Access
Supplementary Figures S1-S23 from Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
2025Open Access
Supplementary Figures S1-S23 from Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
2025Open Access
Ferroptosis: An emerging strategy for managing epithelial ovarian cancer
Biomedicine & Pharmacotherapy·2025· 3 citedOpen Access
Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
Cancer Discovery·2025· 5 citedOpen Access
Advancing Personalized Medicine in Alzheimer’s Disease: Liquid Biopsy Epigenomics Unveil APOE ε4-Linked Methylation Signatures
International Journal of Molecular Sciences·2025· 3 citedOpen Access
Epitranscriptomics in the Glioma Context: A Brief Overview
Cancers·2025Open Access
Chromatin Preparation from Frozen Tissues for Chromatin Immunoprecipitation (ChIP) Assays
Methods in molecular biology·2025
Epigenomic Profiling of Histone Posttranslational Modifications in Frozen Cancer Tissue Using CUT&RUN
Methods in molecular biology·2025
Microglial Replacement Reverses Age-Associated Epigenetic Modifications Despite Accelerating Epigenetic Age
Aging and Disease·2025Open Access
Integration of multi‐omics layers empowers precision diagnosis through unveiling pathogenic mechanisms on maple syrup urine disease
Journal of Inherited Metabolic Disease·2024· 4 citedOpen Access
DNA Methylation Analysis by Bisulfite Pyrosequencing of Mouse Embryonic Fibroblasts with Reprogramming Enhanced by Thyroid Hormones
Methods in molecular biology·2024
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Frequent Co-authors

Manel Esteller(35), Agustín F. Fernández(14), Esteban Ballestar(12), Santiago Ropero(10), Maria F. Paz(7), Jesús Espada(7), Fernando Setién(6), Ana Villar‐Garea(5), Montse Sánchez‐Céspedes(5), María Berdasco(5), Vincenzo Calvanese(5), Pernille Poulsen(4), Allan Vaag(4), Gabriel Capellá(4), Ester Lara(4), Manuel Boix-Chornet(3), Amparo Cano(3), Sebastián Morán(3), David G. Pisano(3), Marta Gut(3)