Stefania Tacconelli

University of Chieti-Pescara — Italy

Medicine · Health Sciences

40h-index5.0kcitations99works10.32yr avg
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Research Topics

Inflammatory mediators and NSAID effects(70), Antiplatelet Therapy and Cardiovascular Diseases(40), Eicosanoids and Hypertension Pharmacology(25), Synthesis of β-Lactam Compounds(12), Pharmacogenetics and Drug Metabolism(9)

Publications99 total

GY971 mitigates inflammation by reducing neutrophil recruitment in cystic fibrosis Ex Vivo and In Vivo models
Journal of Cystic Fibrosis·2025Open Access
Exploiting the 2-(1,3,4,9-tetrahydropyrano[3,4- <i>b</i> ]indol-1-yl)acetic Acid Scaffold to Generate COXTRANs: A New Class of Dual Cyclooxygenase Inhibitors-Thromboxane Receptor Antagonists
Journal of Medicinal Chemistry·2025· 1 citedOpen Access
Janus kinase inhibitors enhance prostanoid biosynthesis in human whole blood in vitro: implications for cardiovascular side effects and prevention strategies
Annals of the Rheumatic Diseases·2025· 4 citedOpen Access
Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity
Nature·2025· 70 citedOpen Access
Evaluating plasma vesicle signatures in chronic coronary artery disease patients for tailored dual therapy with low-dose rivaroxaban and aspirin
Journal of Thrombosis and Haemostasis·2025
New antiplatelet approach: inhibiting Pim kinase to reduce constitutive surface expression of thromboxane A2 receptor
Journal of Thrombosis and Haemostasis·2025· 1 cited
Platelets as crucial players in the dynamic interplay of inflammation, immunity, and cancer: unveiling new strategies for cancer prevention
Frontiers in Pharmacology·2024· 17 citedOpen Access
A sulfonimide derivative of bezafibrate as a dual inhibitor of cyclooxygenase-2 and PPARα
Frontiers in Pharmacology·2024· 1 citedOpen Access
The future of pharmacology and therapeutics of the arachidonic acid cascade in the next decade: Innovative advancements in drug repurposing
Frontiers in Pharmacology·2024· 3 citedOpen Access
Protective Effect of Caffeine and Chlorogenic Acids of Coffee in Liver Disease
Foods·2024· 23 citedOpen Access
POS0002 JANUS KINASE INHIBITORS ENHANCE PROSTANOID BIOSYNTHESIS IN HUMAN WHOLE BLOOD - IMPLICATIONS FOR SIDE-EFFECTS AND PREVENTION STRATEGIES
Annals of the Rheumatic Diseases·2024
Platelets and extracellular vesicles in disease promotion via cellular cross-talk and eicosanoid biosynthesis
Prostaglandins & Other Lipid Mediators·2024· 6 citedOpen Access
Optimizing aspirin dose for colorectal cancer patients through deep phenotyping using novel biomarkers of drug action
Frontiers in Pharmacology·2024· 8 citedOpen Access
Biomarkers of Response to Low-Dose Aspirin in Familial Adenomatous Polyposis Patients
Cancers·2023· 4 citedOpen Access
Tumor-Educated Platelet Extracellular Vesicles: Proteomic Profiling and Crosstalk with Colorectal Cancer Cells
Cancers·2023· 29 citedOpen Access
Cyclooxygenases and platelet functions
Advances in pharmacology·2023· 25 cited
Characterization of the acetylation of cyclooxygenase-isozymes and targeted lipidomics of eicosanoids in serum and colon cancer cells by the new aspirin formulation IP1867B versus aspirin in vitro
Frontiers in Pharmacology·2022· 6 citedOpen Access
The specific deletion of cyclooxygenase-1 in megakaryocytes/platelets reduces intestinal polyposis in Apc mice
Pharmacological Research·2022· 23 cited
Biology and pharmacology of platelet-type 12-lipoxygenase in platelets, cancer cells, and their crosstalk
Biochemical Pharmacology·2022· 25 cited
Inflammation and Cancer: From the Development of Personalized Indicators to Novel Therapeutic Strategies
Frontiers in Pharmacology·2022· 74 citedOpen Access
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Frequent Co-authors

Paola Patrignani(49), Marta L. Capone(21), Annalisa Bruno(17), Maria G. Sciulli(13), Melania Dovizio(13), Emanuela Ricciotti(12), Luigia Di Francesco(10), Carlo Patrono(8), Annalisa Contursi(7), Patrizia Ballerini(6), Giulia Renda(5), Pietro Minuz(5), Francesca Seta(5), Luis A. Garcı́a Rodrı́guez(4), Patrizia Di Gregorio(4), Gabriele Merciaro(4), Carlos Sostres(4), Paola Anzellotti(4), Alessandro Lechi(3), Virgilio Evangelista(3)