Ignacío Pérez de Castro

Instituto de Salud Carlos III — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

34h-index5.2kcitations114works0.42yr avg
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Research Topics

Microtubule and mitosis dynamics(44), Cancer-related Molecular Pathways(20), Cancer, Hypoxia, and Metabolism(20), Ubiquitin and proteasome pathways(13), Epigenetics and DNA Methylation(7)

Publications114 total

CRISPR/Cas9-mediated elimination of the <i>LMNA</i> c.745C&gt;G pathogenic mutation enhances survival and cardiac function in <i>LMNA</i> -associated congenital muscular dystrophy
2025· 1 citedOpen Access
<scp>CRISPR</scp> targeting of <scp> <i>FOXL2</i> </scp> c. <scp>402C</scp> &gt;G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti‐tumoral compounds
Molecular Oncology·2025· 2 citedOpen Access
Author response for "&lt;scp&gt;CRISPR&lt;/scp&gt; targeting of &lt;scp&gt;&lt;i&gt;FOXL2&lt;/i&gt;&lt;/scp&gt; c.&lt;scp&gt;402C&lt;/scp&gt;&gt;G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti‐tumoral compounds"
2024
CRISPR targeting of FOXL2 c.402C&gt;G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds
2024Open Access
Differential sex-dependent role of lncRNAs in cardiomyopathy
Cardiovascular Research·2024Open Access
Review for "Shifting the landscape: Dominant C‐terminal rare missense &lt;scp&gt;&lt;i&gt;FOXL2&lt;/i&gt;&lt;/scp&gt; variants in non‐syndromic primary ovarian failure etiology"
2024
Review for "&lt;i&gt;TPX2&lt;/i&gt; overexpression promotes sensitivity to dasatinib in breast cancer by activating &lt;scp&gt;YAP&lt;/scp&gt; transcriptional signaling"
2024
Review for "&lt;i&gt;TPX2&lt;/i&gt; overexpression promotes sensitivity to dasatinib in breast cancer by activating &lt;scp&gt;YAP&lt;/scp&gt; transcriptional signaling"
2023
Supplementary Video 5 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Figures 1-3 from Tpx2 Controls Spindle Integrity, Genome Stability, and Tumor Development
2023Open Access
Data from Tpx2 Controls Spindle Integrity, Genome Stability, and Tumor Development
2023Open Access
Supplementary Video 3 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Figure 6 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Figure 2 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Video 4 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Figure 7 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Figure Legends from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Figure 7 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Video 1 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
Supplementary Video 6 from Requirements for Aurora-A in Tissue Regeneration and Tumor Development in Adult Mammals
2023Open Access
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Frequent Co-authors

Marcos Malumbres(25), Àngel Pellicer(15), José Fernández‐Piqueras(12), Javier Santos(7), José Fernández‐Piqueras(5), Guillermo de Cárcer(5), María Jiménez(5), Marta Cañamero(5), Gonzalo Fernández‐Miranda(5), María J. Bueno(4), Marta Gómez de Cedrón(4), Ángela Ibáñez(4), J. Sáiz‐Ruiz(4), Trever G. Bivona(3), Mark R. Philips(3), Carlos Blanco(3), Paola Torres(3), Cristina Aguirre‐Portolés(3), Marianna Trakala(3), Bárbara Meléndez(3)