Werner J. Kovacs

ETH Zurich — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index8.8kcitations61works5.02yr avg
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Research Topics

Peroxisome Proliferator-Activated Receptors(36), Melanoma and MAPK Pathways(10), Cholesterol and Lipid Metabolism(10), Cancer, Lipids, and Metabolism(10), Autophagy in Disease and Therapy(8)

Publications59 total

Dysregulated lipid metabolism and hypomyelination in postnatal peroxisome-deficient Pex2 knockout Zellweger mice
Frontiers in Molecular Neuroscience·2026Open Access
Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
Cell Reports·2025· 2 citedOpen Access
The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization
Cell Reports·2024· 13 citedOpen Access
The ULK1 effector BAG2 regulates autophagy initiation by modulating AMBRA1 localization
2023· 1 citedOpen Access
Travelling under pressure - hypoxia and shear stress in the metastatic journey
Clinical & Experimental Metastasis·2023· 22 citedOpen Access
Table S1 from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Table S5 from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Table S3 from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Table S1 from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Data from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Supplementary Data from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Supplementary Data from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Table S5 from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Data from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
Table S3 from A Fatty Acid Oxidation-dependent Metabolic Shift Regulates the Adaptation of <i>BRAF</i>-mutated Melanoma to MAPK Inhibitors
2023Open Access
The peroxisome: an up-and-coming organelle in immunometabolism
Trends in Cell Biology·2022· 99 cited
Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis
Frontiers in Cell and Developmental Biology·2020· 36 citedOpen Access
A Functional SMAD2/3 Binding Site in the PEX11β Promoter Identifies a Role for TGFβ in Peroxisome Proliferation in Humans
Frontiers in Cell and Developmental Biology·2020· 12 citedOpen Access
A Single Metabolite which Modulates Lipid Metabolism Alters Hematopoietic Stem/Progenitor Cell Behavior and Promotes Lymphoid Reconstitution
Stem Cell Reports·2020· 18 citedOpen Access
Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression
Frontiers in Cell and Developmental Biology·2020· 20 citedOpen Access
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Frequent Co-authors

Wilhelm Krek(11), Skaidrite K. Krisans(9), Tanja Eberhart(9), Herbert Stangl(9), Nicola Zamboni(8), Phyllis L. Faust(8), Christophe D. Chabbert(8), Andrea Aloia(6), Daniela Müllhaupt(6), Stefanie Flückiger-Mangual(6), Anja Irmisch(6), Reinhard Dummer(6), Sebastian Jessberger(5), Ana Vukolic(5), Ossia M. Eichhoff(5), Leila T. Alexander(5), Ernesto Scibona(5), Dennie T. Frederick(5), Benchun Miao(5), Chaoran Cheng(5)