Thomas T. Chou

Delaware Technical Community College — United States

Medicine · Health Sciences

14h-index9.1kcitations30works0.02yr avg
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Research Topics

Neuroblastoma Research and Treatments(5), Nerve injury and regeneration(4), HER2/EGFR in Cancer Research(3), Electrochemical Analysis and Applications(3), Axon Guidance and Neuronal Signaling(3)

Publications30 total

A Phase 1 First‐in‐Human Single‐Ascending‐Dose Trial With ESB1609, a Selective Agonist to the Sphingosine‐1‐Phosphate Receptor 5
Clinical Pharmacology in Drug Development·2023· 1 citedOpen Access
Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ-Spondin-Derived Peptide: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose First-in-Human Study
Neurology and Therapy·2022· 11 citedOpen Access
GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 1
2020
GluN1b-GluN2B NMDA receptor in complex with GluN2B antagonist SDZ 220-040, class 2
2020
Modeling Statistical Multiplicity of Infection to Update Methods of Virus Quantification and Infectivity Assays
Bulletin of the American Physical Society·2018
A Phase 1, Single-center, Double-blind, Placebo-controlled Study in Healthy Subjects to Assess the Safety, Tolerability, Clinical Effects, and Pharmacokinetics–Pharmacodynamics of Intravenous Cyclopropyl-methoxycarbonylmetomidate (ABP-700) after a Single Ascending Bolus Dose
Anesthesiology·2017· 37 cited
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Science·2006· 6.5k cited
Pathological Heterogeneity of Frontotemporal Lobar Degeneration with Ubiquitin-Positive Inclusions Delineated by Ubiquitin Immunohistochemistry and Novel Monoclonal Antibodies
American Journal Of Pathology·2006· 321 citedOpen Access
Investigation of the pharmacokinetic and pharmacodynamic interactions between memantine and glyburide/metformin in healthy young subjects: A single-center, multiple-dose, open-label study
Clinical Therapeutics·2005· 26 cited
Neuregulin 1 and Susceptibility to Schizophrenia
The American Journal of Human Genetics·2002· 1.7k citedOpen Access
p38 Mitogen-activated Protein Kinase-independent Induction of gadd45 Expression in Nerve Growth Factor-induced Apoptosis in Medulloblastomas
Journal of Biological Chemistry·2001· 18 citedOpen Access
Biological stability of RNA isolated from RNAlater-treated brain tumor and neuroblastoma xenografts
Medical and Pediatric Oncology·2000· 95 citedOpen Access
Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells
Oncogene·2000· 89 cited
A Novel Apoptotic Pathway Induced by Nerve Growth Factor-mediated TrkA Activation in Medulloblastoma
Journal of Biological Chemistry·2000· 57 citedOpen Access
Biology and signal transduction mechanisms of nerve growth factor-induced apoptosis in medulloblastomas
ScholarlyCommons (University of Pennsylvania)·1999
#509 Effects of TrkA transfection on growth, survival and differentiation of neuroblastoma cells
Journal of Pediatric Hematology/Oncology·1998
Neurotrophin signal transduction in medulloblastoma
Journal of Neuroscience Research·1997· 2 cited
Neurotrophin signal transduction in medulloblastoma
Journal of Neuroscience Research·1997· 26 cited
Nerve Growth Factor Induces Apoptosis in Human Medulloblastoma Cell Lines that Express TrkA Receptors
Journal of Neuroscience·1997· 118 citedOpen Access
ChemInform Abstract: Selective Inhibition of the Tyrosine Kinase pp60c‐src by Analogues of 5,10‐Dihydropyrimido(4,5‐b)quinolin‐4(1H)‐one.
ChemInform·1995
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Frequent Co-authors

John Q. Trojanowski(8), Virginia M.‐Y. Lee(7), Robert L. Dow(5), Bruce M. Bechle(5), C Goddard(4), Eric R. Larson(4), James M. Bobbitt(4), Angelika Eggert(3), Manuela Neumann(2), Deepak M. Sampathu(2), Linda K. Kwong(2), Adam C. Truax(2), Matthew C. Micsenyi(2), Jennifer Bruce(2), Murray Grossman(2), Naohiko Ikegaki(2), Peter Dogterom(2), Khalid Abd‐Elaziz(2), James F. Rusling(2), Barry J. Scheer(2)