Ruth I. Geran

National Cancer Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index1.5kcitations16works0.02yr avg
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Research Topics

Cancer therapeutics and mechanisms(5), Computational Drug Discovery Methods(3), Lung Cancer Treatments and Mutations(2), Analytical Chemistry and Chromatography(2), Cancer Genomics and Diagnostics(2)

Publications16 total

The effectiveness of the anthracycline analog 4′-epidoxorubicin in the treatment of experimental tumors: a review
Investigational New Drugs·1985· 35 cited
Use of a Lactobacillus casei Assay as a Prescreen for Potential Anticancer Agents: An Update Study
Journal of Pharmaceutical Sciences·1984· 4 cited
ChemInform Abstract: POTENTIAL CNS ANTITUMOR AGENTS. VI: AZIRIDINYLBENZOQUINONES III
Chemischer Informationsdienst·1979
Potential CNS Antitumor Agents VI: Aziridinylbenzoquinones III
Journal of Pharmaceutical Sciences·1979· 56 cited
Combination chemotherapy against B 16 melanoma: bleomycin/vinblastine, bleomycin/cis-diamminedichloroplatinum, 5-fluorouracil/BCNU and 5-fluorouracil/methyl-CCNU
Cancer·1978· 12 citedOpen Access
Antagonistic effect of thyroxine against several antitumor agents in murine tumors. Abstr.
The Mouseion at the JAXlibrary (Jackson Laboratory)·1978
Characterization and responsiveness of the Madison 109 lung carcinoma to various antitumor agents.
PubMed·1977· 34 cited
ChemInform Abstract: A STATISTICAL‐HEURISTIC METHOD FOR AUTOMATED SELECTION OF DRUGS FOR SCREENING
Chemischer Informationsdienst·1977
A statistical-heuristic method for automated selection of drugs for screening
Journal of Medicinal Chemistry·1977· 68 cited
Combination chemotherapy against l1210 and p388 leukemia. Melphalan/5-fluorouracil, vincristine/adriamycin, mechlorethamine/ hydroxyurea, and methotrexate/mitomycin c. Abstr.
The Mouseion at the JAXlibrary (Jackson Laboratory)·1977
DON, CONV and DONV—III. Pharmacologic and toxicologic studies
Biochemical Pharmacology·1976· 19 cited
Review of selected experimental brain tumor models used in chemotherapy experiments.
PubMed·1975· 16 cited
ChemInform Abstract: PATTERN RECOGNITION AND STRUCTURE‐ACTIVITY RELATIONSHIP STUDIES, COMPUTER‐ASSISTED PREDICTION OF ANTITUMOR ACTIVITY IN STRUCTURALLY DIVERSE DRUGS IN AN EXPERIMENTAL MOUSE BRAIN TUMOR SYSTEM
Chemischer Informationsdienst·1975· 6 cited
Pattern recognition and structure-activity relation studies. Computer-assisted prediction of antitumor activity in structurally diverse drugs in an experimental mouse brain tumor system
Journal of Medicinal Chemistry·1975· 46 cited
A mouse ependymoblastoma as an experimental model for screening potential antineoplastic drugs.
PubMed·1974· 56 cited
PROTOCOLS FOR SCREENING CHEMICAL AGENTS AND NATURAL PRODUCTS AGAINST ANIMAL TUMORS AND OTHER BIOLOGICAL SYSTEMS
Cancer chemotherapy reports. Part 1·1972· 1.1k cited

Frequent Co-authors

G. F. JUN. HAZARD(4), Philip C. Merker(4), Leo Dudeck(3), George Congleton(3), I Wodinsky(3), Judith A. Mabel(3), Louis Hodes(2), Sidney Richman(2), John S. Driscoll(2), Kenneth C. Chu(2), Robert Feldmann(2), Marvin B. Shapiro(2), Nathaniel H. Greenberg(1), Marylea MacDonald(1), André Schumacher(1), Betty J. Abbott(1), B. J. Abbott(1), James L. Gargus(1), Abraham Goldin(1), John M. Venditti(1)