Jeffrey D. Esko

University of California San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

95h-index42.0kcitations445works3.12yr avg
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Research Topics

Proteoglycans and glycosaminoglycans research(201), Glycosylation and Glycoproteins Research(173), Carbohydrate Chemistry and Synthesis(80), Fibroblast Growth Factor Research(29), Lysosomal Storage Disorders Research(28)

Publications445 total

Tumour acidosis remodels the glycocalyx to control lipid scavenging and ferroptosis
Nature Cell Biology·2026Open Access
Epithelial Heparan Sulfate Promotes <i>Staphylococcus aureus</i> Corneal Infection by Inhibiting Cathelicidins
Proteoglycan Research·2025Open Access
Reply
Ophthalmology·2025Open Access
Antithrombin-binding heparan sulfate is ubiquitously expressed in epithelial cells and suppresses pancreatic tumorigenesis
Journal of Clinical Investigation·2025· 1 citedOpen Access
Tumor Acidosis Remodels the Glycocalyx to Control Lipid Scavenging and Ferroptosis
2025Open Access
Bruch’s membrane heparan sulfate retains lipoproteins in the early stages of age-related macular degeneration
Proceedings of the National Academy of Sciences·2025· 4 citedOpen Access
Global siRNA screen identifies human host factors critical for SARS-CoV-2 replication and late stages of infection
PLoS Biology·2025· 4 citedOpen Access
Release of Extracellular Matrix Components after Human Traumatic Brain Injury
eNeuro·2025Open Access
Novel Application of T1ρ Magnetic Resonance Imaging for Noninvasive Assessment of Bladder Hyperpermeability Biomarkers: A Focus on Glycosaminoglycan Content
Neurourology and Urodynamics·2025
Multi-omic analysis reveals the unique glycan landscape of the blood-brain barrier glycocalyx
2025· 6 citedOpen Access
Endothelial Glycocalyx Turnover in Vascular Health and Disease: Rethinking Endothelial Dysfunction
Annual Review of Biochemistry·2025· 17 citedOpen Access
SARS-CoV-2 infectivity can be modulated through bacterial grooming of the glycocalyx
mBio·2025· 1 citedOpen Access
High-Density Lipoproteins Associated with Age-Related Macular Degeneration in the All of Us Research Program
Ophthalmology·2025· 9 citedOpen Access
Diversity of human salivary heparan sulfate
Glycobiology·2024Open Access
Alteration of Neuropilin-1 and Heparan Sulfate Interaction Impairs Murine B16 Tumor Growth
ACS Chemical Biology·2024· 2 citedOpen Access
Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling
2024· 11 citedOpen Access
Global siRNA Screen Reveals Critical Human Host Factors of SARS-CoV-2 Multicycle Replication
2024· 2 citedOpen Access
Abstract 3937: Investigating the role of fibulin 3 in pancreatic tumorigenesis
Cancer Research·2024
Halofuginone for non-hospitalized adult patients with COVID-19 a multicenter, randomized placebo-controlled phase 2 trial. The HALOS trial
PLoS ONE·2024· 8 citedOpen Access
Transplantation of Wild-Type Hematopoietic Stem and Progenitor Cells Improves Disease Phenotypes in Novel Mucopolysaccharidosis Iiic Mouse Model
SSRN Electronic Journal·2024Open Access
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Frequent Co-authors

Lianchun Wang(8), Ajit Varki(6), Richard D. Cummings(5), Pamela Stanley(4), Gerald W. Hart(4), Joseph R. Bishop(4), Bryan E. Thacker(4), Philip L.S.M. Gordts(4), Ulf Lindahl(4), Jillian R. Brown(4), Roger Lawrence(4), Hudson H. Freeze(3), Carolyn R. Bertozzi(3), Marilynn E. Etzler(3), Mark M. Fuster(3), Thomas Mandel Clausen(3), Jessica Pihl(3), Charles A. Glass(3), Xin Yin(3), Yuan Pu(3)