Lesley Vanes

The Francis Crick Institute — United Kingdom

Immunology and Microbiology · Life Sciences

22h-index2.8kcitations35works1.32yr avg
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Research Topics

Immune Cell Function and Interaction(19), T-cell and B-cell Immunology(16), Epigenetics and DNA Methylation(4), Cell Adhesion Molecules Research(4), Acute Myeloid Leukemia Research(3)

Publications35 total

PD-L2 regulates natural antibody and IL-10 secretion by B-1 cells
2025Open Access
TACI Regulates Marginal Zone B Cell Development
2025Open Access
WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses
Nature Communications·2025· 4 citedOpen Access
T cell migration requires ion and water influx to regulate actin polymerization
Nature Communications·2023· 34 citedOpen Access
B cell–intrinsic requirement for WNK1 kinase in antibody responses in mice
The Journal of Experimental Medicine·2022· 18 citedOpen Access
T cell migration requires ion and water influx to regulate actin polymerization
2022· 4 citedOpen Access
WNK1-dependent water influx is required for CD4 <sup>+</sup> T cell activation and T cell-dependent antibody responses
2022· 3 citedOpen Access
B cell-intrinsic requirement for WNK1 kinase in T cell-dependent antibody responses
2021· 1 citedOpen Access
Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival
The Journal of Experimental Medicine·2020· 58 citedOpen Access
Critical role of WNK1 in MYC-dependent early mouse thymocyte development
eLife·2020· 18 citedOpen Access
Author response: Critical role of WNK1 in MYC-dependent early mouse thymocyte development
2020Open Access
Critical role of WNK1 in MYC-dependent early thymocyte development
2020Open Access
TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK
The Journal of Experimental Medicine·2017· 97 citedOpen Access
Erratum: Corrigendum: WNK1 kinase balances T cell adhesion versus migration in vivo
Nature Immunology·2017· 6 citedOpen Access
Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity
Cell Reports·2016· 74 citedOpen Access
WNK1 kinase balances T cell adhesion versus migration in vivo
Nature Immunology·2016· 74 citedOpen Access
The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway
Immunity·2013· 206 citedOpen Access
Trisomic dose of several chromosome 21 genes perturbs haematopoietic stem and progenitor cell differentiation in Down's syndrome
Oncogene·2010· 46 citedOpen Access
Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome
Blood·2010· 68 citedOpen Access
Function of the Nucleotide Exchange Activity of Vav1 in T Cell Development and Activation
Science Signaling·2009· 76 cited
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Frequent Co-authors

Victor L. J. Tybulewicz(33), Robert Köchl(11), Elizabeth Fisher(8), Harald Hartweger(7), Leonard L. de Boer(6), Joshua Biggs O’May(6), Darryl Hayward(6), Edina Schweighoffer(5), Kathryn Fountain(5), Sandra Ruf(4), Dean Nižetić(4), Jens V. Stein(4), Samuel F. Cooke(3), Francesco Colucci(3), Eleftheria Rosmaraki(3), James P. Di Santo(3), Élise Morice(3), Richard Mitter(3), Miriam Llorián Sopeña(3), Probir Chakravarty(3)