Sam D. Molyneux

Edinburgh Royal Infirmary — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index2.4kcitations20works1.02yr avg
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Research Topics

Glutathione Transferases and Polymorphisms(4), Virus-based gene therapy research(3), Genomics, phytochemicals, and oxidative stress(3), DNA Repair Mechanisms(2), Sarcoma Diagnosis and Treatment(2)

Publications20 total

Mechanical failure after primary internal fixation of unstable ankle fractures –A retrospective observational study
Foot and Ankle Surgery·2025· 1 cited
Author Correction: Human somatic cell mutagenesis creates genetically tractable sarcomas
Nature Genetics·2020Open Access
Cross-species genomics identifies DLG2 as a tumor suppressor in osteosarcoma
Oncogene·2018· 78 citedOpen Access
RANKL blockade prevents and treats aggressive osteosarcomas
Science Translational Medicine·2015· 88 cited
A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis
Nature Genetics·2015· 244 cited
Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
Cancer Cell·2015· 49 citedOpen Access
Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression
Cancer Cell·2015· 949 citedOpen Access
Erratum: Corrigendum: Human somatic cell mutagenesis creates genetically tractable sarcomas
Nature Genetics·2014Open Access
Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state
Nature Cell Biology·2014· 189 cited
Human somatic cell mutagenesis creates genetically tractable sarcomas
Nature Genetics·2014· 28 cited
PKA signaling drives mammary tumorigenesis through Src
Oncogene·2014· 82 cited
Estrogen controls the survival of BRCA1-deficient cells via a PI3K–NRF2-regulated pathway
Proceedings of the National Academy of Sciences·2014· 121 citedOpen Access
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival
The Journal of Cell Biology·2013· 12 cited
BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival
The Journal of Experimental Medicine·2013· 281 citedOpen Access
Abstract 398: Genome-wide comparison of matched canine osteosarcoma primary tumours and metastases by array comparative genomic hybridization.
Cancer Research·2013
Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis
Immunity·2012· 123 citedOpen Access
Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice
Journal of Clinical Investigation·2010· 99 citedOpen Access
Abstract A6: Dissecting mechanisms of RANKL dependency in osteosarcoma
Cancer Research·2009· 1 cited
The identification of topics for research that are important to people with ulcerative colitis
European Journal of Gastroenterology & Hepatology·2006· 31 cited
Safety and immunogenicity of the candidate malaria vaccines FP9 ME-TRAP and MVA METRAP in semi-immune adult males [MIM-OK-87312]
Oxford University Research Archive (ORA) (University of Oxford)·2005

Frequent Co-authors

Rama Khokha(16), Tak W. Mak(8), Isaac S. Harris(7), Hal K. Berman(7), Yang Shao(7), Paul Waterhouse(6), Chiara Gorrini(5), David W. Cescon(5), Andrew Wakeham(5), Dirk Brenner(4), Andrew Elia(4), Mathieu Lupien(4), Marco A. Di Grappa(4), Qinglian Tang(4), Satoshi Inoue(3), Wanda Y. Li(3), Purna A. Joshi(3), Mona L. Gauthier(3), Alexander G. Beristain(3), Trevor D. McKee(3)