Herman Devijver

KU Leuven — Belgium

Medicine · Health Sciences

24h-index2.4kcitations49works0.02yr avg
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Research Topics

Alzheimer's disease research and treatments(31), Neuroscience and Neuropharmacology Research(12), Wnt/β-catenin signaling in development and cancer(8), Neuroinflammation and Neurodegeneration Mechanisms(7), Prion Diseases and Protein Misfolding(5)

Publications49 total

GSK3β activity alleviates epileptogenesis and limits GluA1 phosphorylation
EBioMedicine·2018· 32 citedOpen Access
GSK3β Activity Alleviates Epileptogenesis and Limits GluA1 Phosphorylation
SSRN Electronic Journal·2018Open Access
GSK3β Controls mTOR and Prosurvival Signaling in Neurons
Molecular Neurobiology·2017· 22 citedOpen Access
Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope
Journal of Alzheimer s Disease·2016· 11 citedOpen Access
Late phase LTD in transgenic mouse models of AD and tauopathies as a synaptic readout of imbalanced tau phosphorylation
2016
Aggravated deficits in hippocampal synaptic plasticity and hippocampus-dependent memory by increased GSK3ß activity in double transgenic (GSK3β/Tau301L) mice
2016
Restoration of Impaired L-LTD by GSK3 Inhibition of PP2A Activation in Tau.P301L Mice that Model Tauopathy of Alzheimer's Disease
2016
GSK-3β and MMP-9 Cooperate in the Control of Dendritic Spine Morphology
Molecular Neurobiology·2016· 45 citedOpen Access
No increased inflammatory response in ACI-35 treated Tau.P301L mice.
Figshare·2015Open Access
ACI-35 elicits robust and specific antisera against Tau in wild-type and Tau.P301L mice.
Figshare·2015Open Access
P1‐047: Epileptogenicity and precocious mortality of bigenic biat mice that express amyloid and tau
Alzheimer s & Dementia·2015Open Access
Terminal hypothermic <scp>T</scp>au.<scp>P</scp>301<scp>L</scp> mice have increased Tau phosphorylation independently of glycogen synthase kinase 3α/β
European Journal of Neuroscience·2014· 12 cited
Phosphorylation of protein Tau by GSK3β prolongs survival of bigenic Tau.P301L×GSK3β mice by delaying brainstem tauopathy
Neurobiology of Disease·2014· 15 citedOpen Access
Early Structural and Functional Defects in Synapses and Myelinated Axons in Stratum Lacunosum Moleculare in Two Preclinical Models for Tauopathy
PLoS ONE·2014· 44 citedOpen Access
Increasing Brain Protein O-GlcNAc-ylation Mitigates Breathing Defects and Mortality of Tau.P301L Mice
PLoS ONE·2013· 91 citedOpen Access
Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy
PLoS ONE·2013· 249 citedOpen Access
O2–06–04: A liposomal anti‐phospho‐tau vaccine demonstrates higher immunogenicity and specificity than a classical peptide vaccine approach
Alzheimer s & Dementia·2013Open Access
P2–414: O‐GlcNAc‐ase inhibitor improves the clinical conditions of Alzheimer's disease mice
Alzheimer s & Dementia·2013
Neurological characterization of mice deficient in GSK3α highlight pleiotropic physiological functions in cognition and pathological activity as Tau kinase
Molecular Brain·2013· 41 citedOpen Access
Tauopathy Differentially Affects Cell Adhesion Molecules in Mouse Brain: Early Down-Regulation of Nectin-3 in Stratum Lacunosum Moleculare
PLoS ONE·2013· 43 citedOpen Access
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Frequent Co-authors

Fred Van Leuven(39), Peter Borghgraef(38), Benoit Lechat(23), Tomasz Jaworski(14), Ilse Dewachter(14), Clara Theunis(13), Natàlia Crespo‐Biel(10), Hervé Maurin(10), Valérie Gafner(8), Maria Pihlgren(8), Oskar Adolfsson(8), Nathalie Chuard(7), Andrea Pfeifer(7), Andreas Muhs(7), Yvan Saeys(7), David Demedts(7), S. Croes(6), David T. Hickman(6), Gérard Hilaire(6), David Muyllaert(5)