Samir A. Kulkarni

Materials Science · Physical Sciences

12h-index760citations22works0.02yr avg
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Research Topics

Crystallization and Solubility Studies(13), Innovative Microfluidic and Catalytic Techniques Innovation(7), Analytical Chemistry and Chromatography(4), nanoparticles nucleation surface interactions(4), Computational Drug Discovery Methods(3)

Publications22 total

High-Throughput Generation of Droplet-Templated Amorphous Solid Dispersions Using Continuous Antisolvent Extraction
SSRN Electronic Journal·2025Open Access
Synthesis of Nirmatrelvir: Design and Optimization of an Efficient Telescoped Amidation–Dehydration Sequence
Organic Process Research & Development·2023· 14 cited
Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months
ACS Central Science·2023· 37 citedOpen Access
Early Clinical Development of Lufotrelvir as a Potential Therapy for COVID-19
Organic Process Research & Development·2023· 24 cited
Cross-Pharma Collaboration for the Development of a Simulation Tool for the Model-Based Digital Design of Pharmaceutical Crystallization Processes (CrySiV)
Crystal Growth & Design·2021· 19 cited
CCDC 2099928: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Streamlined Synthesis of a Bicyclic Amine Moiety Using an Enzymatic Amidation and Identification of a Novel Solid Form
Organic Process Research & Development·2021· 4 cited
Understanding Polymorph Selection of Sulfamerazine in Solution
Crystal Growth & Design·2019· 16 cited
Two-Stage Crystallizer Design for High Loading of Poorly Water-Soluble Pharmaceuticals in Porous Silica Matrices
Crystals·2017· 11 citedOpen Access
Two-Stage Crystallizer Design for High Loading of Poorly Water-Soluble Pharmaceuticals in Porous Silica Matrices
DSpace@MIT (Massachusetts Institute of Technology)·2017Open Access
Methods for Nano-Crystals Preparation
NATO science for peace and security series. A, Chemistry and biology·2017· 12 cited
Reversible control of solubility using functionalized nanoparticles
Chemical Communications·2016· 9 cited
The Use of Cooling Crystallization in an Ionic Liquid System for the Purification of Pharmaceuticals
Crystal Growth & Design·2015· 39 cited
Self-Association during Heterogeneous Nucleation onto Well-Defined Templates
Langmuir·2014· 27 cited
Polymorphism Control through a Single Nucleation Event
Crystal Growth & Design·2014· 32 cited
Template-Induced Nucleation of Isonicotinamide Polymorphs
Crystal Growth & Design·2014· 38 cited
Crystal Nucleation Kinetics from Induction Times and Metastable Zone Widths
Crystal Growth & Design·2013· 201 cited
A new view on the metastable zone width during cooling crystallization
Chemical Engineering Science·2012· 145 cited
Isonicotinamide self-association: the link between solvent and polymorph nucleation
Chemical Communications·2012· 132 citedOpen Access
Polymorph discovery by controlling the self-association in solution
2012
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Frequent Co-authors

Joop H. ter Horst(6), Allan S. Myerson(6), Hugo Meekes(4), Andrzej Stankiewicz(4), Taegyo Lee(4), Gerald A. Weisenburger(4), Christophe Allais(3), Amber M. Johnson(3), JH ter Horst(3), Somnath S. Kadam(2), Cameron C. Weber(2), Christina G. Connor(2), Nga M.(2), Johnny W. Lee(2), Emma L. McInturff(2), Jared L. Piper(2), John A. Ragan(2), D.W. Place(2), Leia M. Dwyer(2), Luzdary Ruelas(2)