Sabine J. van Dijk

University of California, Davis — United States

Medicine · Health Sciences

14h-index984citations29works0.02yr avg
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Research Topics

Cardiomyopathy and Myosin Studies(22), Cardiovascular Effects of Exercise(14), Muscle Physiology and Disorders(6), Cardiac electrophysiology and arrhythmias(4), Viral Infections and Immunology Research(4)

Publications29 total

Hypertrophic cardiomyopathy in purpose-bred cats with the A31P mutation in cardiac myosin binding protein-C
Scientific Reports·2023· 10 citedOpen Access
Diminished β-Adrenergic Response in Protein Kinase D Knock-Out Cardiomyocytes
Biophysical Journal·2020Open Access
Building a Professional Identity and an Academic Career Track in Translational Medicine
Frontiers in Medicine·2019· 9 citedOpen Access
Point mutations in the tri-helix bundle of the M-domain of cardiac myosin binding protein-C influence systolic duration and delay cardiac relaxation
Journal of Molecular and Cellular Cardiology·2018· 23 citedOpen Access
In Situ Replacement of cMyBP-C N'-Terminal Domains using the Novel Spy-C Method
Biophysical Journal·2018Open Access
Reduced Binding of the M-Domain of Cardiac Myosin Binding Protein C to Actin Impairs the Ability of the Heart to Respond to Chronic Stress
Biophysical Journal·2017Open Access
Abstract 85: Interactions Between Cardiac Myosin Binding Protein C and Actin Contribute to the Regulation of Cardiac Contraction
Circulation Research·2016
Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes
Journal of Molecular and Cellular Cardiology·2016· 149 citedOpen Access
The A31P missense mutation in cardiac myosin binding protein C alters protein structure but does not cause haploinsufficiency
Archives of Biochemistry and Biophysics·2016· 23 citedOpen Access
Normal cardiac contraction in mice lacking the proline–alanine rich region and C1 domain of cardiac myosin binding protein C
Journal of Molecular and Cellular Cardiology·2015· 8 citedOpen Access
The Physiological Relevance of Interactions between cMyBP-C and Actin Studied in a Transgenic Mouse Model
Biophysical Journal·2015
The A31P Hcm Mutation in cMyBP-C Disrupts the Structure of the C0 Domain But Does Not Cause Haploinsufficiency in a Population of Older Cats Heterozygous for the A31P Allele
Biophysical Journal·2015Open Access
Earning stripes: myosin binding protein-C interactions with actin
Pflügers Archiv - European Journal of Physiology·2014· 55 citedOpen Access
Preserved cross-bridge kinetics in human hypertrophic cardiomyopathy patients with MYBPC3 mutations
Pflügers Archiv - European Journal of Physiology·2013· 14 cited
Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy
Cardiovascular Research·2013· 105 citedOpen Access
Cardiomyocyte Hypertrophy and Reduced Myofibril Density Underlie Decreased Maximal Force Generating Capacity in Familial Hypertrophic Cardiomyopathy
Biophysical Journal·2012Open Access
Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function
Circulation Heart Failure·2011· 122 citedOpen Access
The HCM-Associated Cardiac Troponin T Mutation K273N Accelerates Tension Generation and Relaxation in Human Cardiac Myofibrils
Biophysical Journal·2011Open Access
Reduced Maximal Force and Increased Ca2+-Sensitivity of Human Myofilaments Harbouring the HCM-Associated Cardiac Troponin T Mutation K273N
Biophysical Journal·2011Open Access
The development of familial hypertrophic cardiomyopathy: from mutation to bedside
European Journal of Clinical Investigation·2010· 25 cited
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Frequent Co-authors

Samantha P. Harris(11), Cristobal G. dos Remedios(10), Ger J.M. Stienen(10), Jolanda van der Velden(10), Dennis Dooijes(5), Michelle Michels(5), Folkert J. ten Cate(5), Kristina B. Kooiker(5), Patricia A. C. Specht(4), Howard J. Jacob(4), Marjon van Slegtenhorst(3), Kristina L. Bezold(3), Stacy Mazzalupo(3), Jozef Lazar(3), Abraham P. Provoost(3), Jos M. J. Lamers(2), Lucie Carrier(2), E. Rosalie Paalberends(2), Nicky M. Boontje(2), Nicoletta Piroddi(2)