Charles D. Schwieters

National Institutes of Health — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

49h-index12.7kcitations191works10.62yr avg
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Research Topics

Protein Structure and Dynamics(80), Enzyme Structure and Function(60), Advanced NMR Techniques and Applications(45), RNA and protein synthesis mechanisms(24), RNA Research and Splicing(17)

Publications191 total

Determining structures of RNA conformers using AFM and deep neural networks
Nature·2024· 34 citedOpen Access
Automated fibril structure calculations in Xplor-NIH
Structure·2024· 1 citedOpen Access
Integrating <sup>19</sup>F Distance Restraints for Accurate Protein Structure Determination by Magic Angle Spinning NMR Spectroscopy
Journal of the American Chemical Society·2024· 5 citedOpen Access
CD28 hinge used in chimeric antigen receptor (CAR) T-cells exhibits local structure and conformational exchange amidst global disorder
Communications Biology·2024· 5 citedOpen Access
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins
UNC Libraries·2024Open Access
Quantitative Characterization of Chain-Flipping of Acyl Carrier Protein of <i>Escherichia coli</i> Using Chemical Exchange NMR
Journal of the American Chemical Society·2024· 1 citedOpen Access
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue
Nature Communications·2024· 63 citedOpen Access
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins
Nature Communications·2024· 7 citedOpen Access
<scp>Xplor‐NIH</scp>: Better parameters and protocols for <scp>NMR</scp> protein structure determination
Protein Science·2024· 15 citedOpen Access
Restraint validation of biomolecular structures determined by NMR in the Protein Data Bank
Structure·2024· 6 citedOpen Access
Study of Biomolecular Structure and Dynamics with Xplor-NIH
2024
Restraint Validation of Biomolecular Structures Determined by NMR in the Protein Data Bank
2024· 1 citedOpen Access
Automated Fibril Structure Calculation in Xplor-NIH
SSRN Electronic Journal·2024Open Access
Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal
Nature·2023· 82 citedOpen Access
Determining structures of individual RNA conformers using atomic force microscopy images and deep neural networks
2023· 3 citedOpen Access
Reduced dynamic complexity allows structure elucidation of an excited state of KRASG13D
Communications Biology·2023· 16 citedOpen Access
Interaction of the bacterial division regulator MinE with lipid bicelles studied by NMR spectroscopy
Journal of Biological Chemistry·2023· 1 citedOpen Access
Visualizing RNA conformational and architectural heterogeneity in solution
Nature Communications·2023· 54 citedOpen Access
Quantitative analysis of sterol-modulated monomer–dimer equilibrium of the β <sub>1</sub> -adrenergic receptor by DEER spectroscopy
Proceedings of the National Academy of Sciences·2023· 17 citedOpen Access
Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue
2023· 9 citedOpen Access
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Frequent Co-authors

G. Marius Clore(22), Chad M. Rienstra(6), Xiaobing Zuo(6), Yun‐Xing Wang(6), Ping Yu(5), John Kuszewski(4), Jinbu Wang(4), Rodolfo Ghirlando(4), Dominik Berthold(3), David M. Tiede(3), Nico Tjandra(2), Junxia Lu(2), Wei Qiang(2), Wai‐Ming Yau(2), Stephen C. Meredith(2), Robert Tycko(2), Andrew J. Nieuwkoop(2), Alexander M. Barclay(2), Junji Iwahara(2), Jason R. Stagno(2)