Jörg Scheuermann

ETH Zurich — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

45h-index5.8kcitations127works4.52yr avg
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Research Topics

Chemical Synthesis and Analysis(78), Monoclonal and Polyclonal Antibodies Research(72), Click Chemistry and Applications(33), Advanced biosensing and bioanalysis techniques(27), RNA and protein synthesis mechanisms(14)

Publications127 total

A tailored enzyme cascade facilitates DNA-encoded library technology and gives access to a broad substrate scope
2025· 1 citedOpen Access
The Influence of Single-Stranded or Double-Stranded DNA Tags on Ligand Binding Affinity in DNA-Encoded Libraries
Analytical Chemistry·2025· 1 cited
Native Mass Spectrometry Facilitates Hit Validation in DNA‐Encoded Library Technology
Angewandte Chemie International Edition·2025· 5 citedOpen Access
Native Massenspektrometrie erleichtert die Hit‐Validierung in der DNA‐Encoded Library Technologie
Angewandte Chemie·2025Open Access
Flexibility-tuning of dual-display DNA-encoded chemical libraries facilitates cyclic peptide ligand discovery
Nature Communications·2025· 9 citedOpen Access
Structure-based design and evaluation of tyrosinase inhibitors targeting both human and mushroom isozymes
RSC Medicinal Chemistry·2025· 2 citedOpen Access
DNA-encoded chemical libraries on stage
Nature Chemical Biology·2024· 5 cited
Highly pure DNA-encoded chemical libraries by dual-linker solid-phase synthesis
Science·2024· 25 cited
Asymmetry of Dual-Display DNA-Encoded Chemical Libraries
Bioconjugate Chemistry·2024· 1 cited
4.1 Selections by Affinity Capture on Solid Support
2024
1 Introduction
2024
DNA-Encoded Libraries
2023· 3 cited
Ex vivo mass spectrometry-based biodistribution analysis of an antibody-Resiquimod conjugate bearing a protease-cleavable and acid-labile linker
Frontiers in Pharmacology·2023· 4 citedOpen Access
Advancing small-molecule drug discovery by encoded dual-display technologies
Trends in Pharmacological Sciences·2023· 17 cited
Author response for "Impact of library input on the hit discovery rate in DNA-Encoded Chemical Library selections"
2023
Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase
European Journal of Medicinal Chemistry·2023· 12 citedOpen Access
Site-Specific Chemical Modification of a Cytokine Mimic for Small Molecule-Based Tumor Targeting
Bioconjugate Chemistry·2023
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition
Nature Chemistry·2023· 28 cited
RGD Cyclopeptide Equipped with a Lysine‐Engaging Salicylaldehyde Showing Enhanced Integrin Affinity and Cell Detachment Potency
Chemistry - A European Journal·2023· 4 citedOpen Access
Impact of library input on the hit discovery rate in DNA-encoded chemical library selections
Chemical Science·2023· 8 citedOpen Access
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Frequent Co-authors

Dario Neri(48), Christoph E. Dumelin(12), Samu Melkko(11), Luca Mannocci(10), Yixin Zhang(9), Raphael M. Franzini(8), Fabian Buller(8), Nicholas Favalli(6), Florent Samain(6), Moreno Wichert(4), Willy Decurtins(4), Gabriele Bassi(4), Jonathan Hall(4), Markus Leimbacher(3), Yizhou Li(3), Davor Bajic(3), Angela Nauer(3), Mauro Zimmermann(3), Peter J. Brown(3), S. Gräslund(3)