Monica Soto‐Velasquez

Purdue University West Lafayette — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index256citations15works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(8), Neuropeptides and Animal Physiology(5), Phosphodiesterase function and regulation(5), Pain Mechanisms and Treatments(3), Peptidase Inhibition and Analysis(2)

Publications15 total

Optimization of a Pyrimidinone Series for Selective Inhibition of Ca <sup>2+</sup> /Calmodulin-Stimulated Adenylyl Cyclase 1 Activity for the Treatment of Chronic Pain
Journal of Medicinal Chemistry·2022· 4 citedOpen Access
Optimization of a Pyrimidinone Series for Selective Inhibition of Ca2+/Calmodulin-Stimulated Adenylyl Cyclase 1 Activity for the Treatment of Chronic Pain
2021Open Access
Optimization of a Pyrimidinone Series for Selective Inhibition of Ca2+/Calmodulin-Stimulated Adenylyl Cyclase 1 Activity for the Treatment of Chronic Pain
2021Open Access
Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases
European Journal of Medicinal Chemistry·2021· 9 citedOpen Access
Genome-Wide Small Interfering RNA Screening Reveals a Role for Cullin3–Really Interesting New Gene Ligase Signaling in Heterologous Sensitization of Adenylyl Cyclase
Journal of Pharmacology and Experimental Therapeutics·2019· 9 citedOpen Access
Identification of Novel Adenylyl Cyclase 5 (AC5) Signaling Networks in D1 and D2 Medium Spiny Neurons using Bimolecular Fluorescence Complementation Screening
Cells·2019· 34 citedOpen Access
Optimization of a 1,3,4-oxadiazole series for inhibition of Ca2+/calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain
European Journal of Medicinal Chemistry·2018· 35 citedOpen Access
Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from <i>Bordetella pertussis</i> and <i>Bacillus anthracis</i>
ChemMedChem·2018· 12 citedOpen Access
A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling
Molecular Pharmacology·2018· 45 citedOpen Access
A Novel CRISPR/Cas9‐Based Cellular Model to Explore Adenylyl Cyclase and Cyclic AMP Signaling
The FASEB Journal·2018
Novel Tools to Study Modulation of Adenylyl Cyclase Isoforms
Purdue e-Pubs (Purdue University)·2018
Synthesis of α‐Branched Acyclic Nucleoside Phosphonates as Potential Inhibitors of Bacterial Adenylate Cyclases
ChemMedChem·2017· 11 cited
Identification of FDA-Approved Small Molecules Capable of Disrupting the Calmodulin–Adenylyl Cyclase 8 Interaction through Direct Binding to Calmodulin
ACS Chemical Neuroscience·2017· 20 cited
Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties
Science Signaling·2017· 64 citedOpen Access
Molecular Modeling Evaluation of the Enantiomers of a Novel Adenylyl Cyclase 2 Inhibitor
Journal of Chemical Information and Modeling·2017· 13 cited

Frequent Co-authors

Val J. Watts(14), Michael P. Hayes(7), Karin F.K. Ejendal(5), Jatinder Kaur(4), Daniel P. Flaherty(4), Jan Skácel(3), Martin Dračínský(3), Helena Mertlíková‐Kaiserová(3), Zlatko Janeba(3), Justin LaVigne(3), Heath Miller(3), Carmen Dessauer(2), Richard M. van Rijn(2), Aktan Alpsoy(2), Emily C. Dykhuizen(2), Zhong Jie Ding(2), Markus A. Lill(2), Michal Česnek(2), Markéta Šmídková(2), Jason Scott(2)