Karl Garsha

Roche (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index448citations26works0.02yr avg
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Research Topics

Advanced Fluorescence Microscopy Techniques(8), Prostate Cancer Treatment and Research(6), Molecular Biology Techniques and Applications(4), Cell Image Analysis Techniques(4), Glycosylation and Glycoproteins Research(3)

Publications26 total

Activity of trastuzumab emtansine (T-DM1) in 3D cell culture
Breast Cancer Research and Treatment·2021· 13 citedOpen Access
Abstract 29: Activity of trastuzumab emtansine (T-DM1) in 3D cell culture
Cancer Research·2019
Abstract 29: Activity of trastuzumab emtansine (T-DM1) in 3D cell culture
Tumor Biology·2019Open Access
Fully automated 5-plex fluorescent immunohistochemistry with tyramide signal amplification and same species antibodies
Laboratory Investigation·2017· 99 citedOpen Access
Mapping cancer signaling networks by an integrated multiplexed tissue imaging platform
TECHNOLOGY·2016· 4 cited
Abstract 5117: An automated 5-plex fluorescent immunohistochemistry enabled characterization of PD-L1 expression and tumor infiltrating immune cells in lung and bladder cancer specimens
Cancer Research·2016
A technique for relative quantitation of cancer biomarkers in formalin‐fixed, paraffin‐embedded (FFPE) tissue using stable‐isotope‐label based mass spectrometry imaging (SILMSI)
Journal of Mass Spectrometry·2015· 9 cited
Multi-modal contrast of tissue anatomy enables correlative biomarker imaging
Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE·2015· 1 cited
Automated 5-plex fluorescent immunohistochemistry with tyramide signal amplification using antibodies from the same species
Journal for ImmunoTherapy of Cancer·2015· 1 citedOpen Access
Multiplexed protein and gene profiling of circulating tumor cells (CTCs) in metastatic castration-resistant prostate cancer (mCRPC) using automated immunofluorescence and fluorescence in situ hybridization.
Journal of Clinical Oncology·2013· 1 cited
Development of a molecular profiling assay for circulating tumor cells (CTCs) utilizing automated multiplexed in situ hybridization for metastatic castrate-resistant prostate cancer (mCRPC).
Journal of Clinical Oncology·2012
937 Concordance of ERG gene rearrangements and ERG protein expression in PIN lesions in prostate needle biopsies
European Urology Supplements·2012
Partial plasma cell differentiation as a mechanism of lost major histocompatibility complex class II expression in diffuse large B-cell lymphoma
Blood·2011· 61 citedOpen Access
Abstract 2227: Concordance of <i>ERG</i> gene rearrangements and <i>ERG</i> protein expression in low grade PIN lesions in prostate needle biopsies
Cancer Research·2011
Abstract 2218: Integrated diagnostic methods for detection of multiple gene rearrangements in prostate cancer tissue specimens
Cancer Research·2011
527 INTEGRATED DIAGNOSTIC METHODS FOR DETECTION OF MULTIPLE GENE REARRANGEMENTS IN PROSTATE CANCER TISSUE SPECIMENS
European Urology Supplements·2011
Testing mutual exclusivity of ETS rearranged prostate cancer
Laboratory Investigation·2010· 75 citedOpen Access
Quantitative Fluorescence Microscopy: Considerations and Controls
Springer series on fluorescence·2008· 6 cited
The “F” Words
Imaging & Microscopy·2007
A Comment on using FLIM with FRET
Microscopy Today·2006Open Access
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Frequent Co-authors

Dea Nagy(8), Gary A. Pestano(7), Ubaradka G. Sathyanarayana(6), Ryan Dittamore(6), Francesca Demichelis(5), Mark A. Rubin(5), Janice Riley(4), Michael Otter(4), Connie C. Cortez(4), Krystyn Pozarowski(4), Antony Hubbard(3), Tobin Jones(3), Adriana Racolta(3), Srabani Bhaumik(3), Lei Tang(3), Maria A. Svensson(3), Jean Z. Boyer(3), Gail D. Lewis Phillips(3), Hiro Nitta(3), Brittany Admire(3)