Giovanni Sorrentino

University of Trieste — Italy

Medicine · Health Sciences

16h-index3.2kcitations41works1.92yr avg
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Research Topics

Liver physiology and pathology(11), Hippo pathway signaling and YAP/TAZ(9), Liver Disease Diagnosis and Treatment(8), Pancreatic function and diabetes(7), Lipid metabolism and biosynthesis(6)

Publications41 total

Human liver organoids uncover ductular reaction in Wolman disease and inform gene therapy design
2025Open Access
An organotypic model of ductular reaction reveals a mevalonate-dependent vulnerability in reactive biliary cells
Cell Reports·2025Open Access
Next-Generation Hydrogels for Biliary Organoid Engineering
Pharmaceuticals·2025Open Access
Differential expression of Complement regulators in preeclampsia and healthy pregnancy: trophoblast organoids as a model to recapitulate disease phenotype
Journal of Reproductive Immunology·2025
Thermally Cured Gelatin-Methacryloyl Hydrogels Form Mechanically Modulating Platforms for Cell Studies
Biomacromolecules·2025· 4 citedOpen Access
WED-333-YI Recreating Wolman disease in human liver organoids: a new model for pathophisiology and therapeutic exploration
Journal of Hepatology·2025
Microenvironmental control of the ductular reaction: balancing repair and disease progression
Cell Death and Disease·2025· 10 citedOpen Access
FRI-167-YI Modelling wolman disease using genetically engineered human liver organoids
Journal of Hepatology·2024· 1 cited
Author response: Hepatic lipid overload triggers biliary epithelial cell activation via E2Fs
2023Open Access
Author Response: Hepatic lipid overload potentiates biliary epithelial cell activation via E2Fs
2022Open Access
Hepatic lipid overload triggers biliary epithelial cell activation via E2Fs
eLife·2022· 6 citedOpen Access
Reviewer #2 (Public Review): Hepatic lipid overload potentiates biliary epithelial cell activation via E2Fs
2022Open Access
Reviewer #1 (Public Review): Hepatic lipid overload potentiates biliary epithelial cell activation via E2Fs
2022Open Access
Hepatic lipid overload potentiates biliary epithelial cell activation via E2Fs
2022· 1 citedOpen Access
Hepatic lipid overload potentiates biliary epithelial cell activation via E2Fs
2022Open Access
Mechano-modulatory synthetic niches for liver organoid derivation
Nature Communications·2020· 205 citedOpen Access
Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration
Gastroenterology·2020· 363 citedOpen Access
L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
Diabetes·2020· 75 citedOpen Access
Studio osservazionale sull’adesione alla pratica vaccinale degli Operatori Sanitari dell’AOU San Giovanni di Dio e Ruggi d’Aragona
2020
Mechano-modulatory synthetic niches for liver organoid derivation
2019· 13 citedOpen Access
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Frequent Co-authors

Giannino Del Sal(19), Kristina Schoonjans(11), Ece Yıldız(10), Silvio Bicciato(9), Alessia Perino(8), Gaby El Alam(8), Antoine Jalil(7), Pierre‐Damien Denechaud(7), Katharina Huber(7), Lluís Fajas(7), Johan Auwerx(7), Alessandro Zannini(6), Antonio Rosato(5), Miguel Mano(4), Eleonora Ingallina(4), Silvano Piazza(4), Rebecca Bertolio(4), Fiamma Mantovani(4), Davide Selvestrel(4), Beatrice Anfuso(4)