Teresa Fernandes‐Alnemri

Thomas Jefferson University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

59h-index25.6kcitations80works0.02yr avg
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Research Topics

Cell death mechanisms and regulation(36), Inflammasome and immune disorders(29), interferon and immune responses(18), NF-κB Signaling Pathways(9), Immune Response and Inflammation(8)

Publications80 total

Pyroptosis Modulates Multiple Immune Cell Populations in Targeted Therapy–Treated Melanoma
Cancer Immunology Research·2025Open Access
Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis
Nature Communications·2021· 98 citedOpen Access
Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation
Nature Communications·2019· 789 citedOpen Access
SUMO-mediated regulation of NLRP3 modulates inflammasome activity
Nature Communications·2018· 218 citedOpen Access
Double-Strand DNA Sensing Aim2 Inflammasome Regulates Atherosclerotic Plaque Vulnerability
Circulation·2018· 105 citedOpen Access
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
Nature Communications·2017· 1.4k citedOpen Access
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
Nature Communications·2015· 246 citedOpen Access
Non‐transcriptional regulation of NLRP3 inflammasome signaling by IL‐4
Immunology and Cell Biology·2015· 39 citedOpen Access
Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function
The Journal of Immunology·2014· 198 citedOpen Access
The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity
The Journal of Immunology·2013· 260 citedOpen Access
Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome
The Journal of Immunology·2013· 230 citedOpen Access
Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome
Journal of Biological Chemistry·2013· 36 citedOpen Access
Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death
Cancer Letters·2013· 24 citedOpen Access
Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death
2013
Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome
2013· 1 cited
A novel role for the mitochondrial HTRA2/OMI protease in aging
Autophagy·2012· 52 citedOpen Access
Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging
Cell Death and Differentiation·2012· 80 cited
Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation
Journal of Biological Chemistry·2012· 736 citedOpen Access
Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to <i>Streptococcus pneumoniae</i> Infection
The Journal of Immunology·2011· 160 citedOpen Access
Cutting Edge: Mutation of <i>Francisella tularensis mviN</i> Leads to Increased Macrophage Absent in Melanoma 2 Inflammasome Activation and a Loss of Virulence
The Journal of Immunology·2010· 75 citedOpen Access
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Frequent Co-authors

Emad S. Alnemri(43), Srinivasa M. Srinivasula(24), Pinaki Datta(13), Gerald Litwack(10), Manzoor Ahmad(10), Je‐Wook Yu(8), Jianghong Wu(6), R.P. Hegde(6), Christine A. Juliana(5), Zhijia Zhang(5), Yigong Shi(4), Seokwon Kang(4), Katherine A. Fitzgerald(3), Corey Rogers(3), Lindsey Mayes(3), Emad S. Alnemri(3), Robert C. Armstrong(3), Yuri Lazebnik(3), Leobaldo Solórzano(3), Jean‐Luc Poyet(3)