Gabriel Cornilescu

Frederick National Laboratory for Cancer Research — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

33h-index9.9kcitations97works9.72yr avg
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Research Topics

Protein Structure and Dynamics(27), Enzyme Structure and Function(21), RNA and protein synthesis mechanisms(15), Advanced NMR Techniques and Applications(8), Antimicrobial Resistance in Staphylococcus(7)

Publications97 total

Natural Product Graveoline Modulates Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Membrane Association: Insights from Advanced Spectroscopic Studies
ACS Pharmacology & Translational Science·2024· 2 citedOpen Access
Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties
Science Advances·2024· 27 citedOpen Access
1D and 2D NMR for KRAS:Ligand Binding
Methods in molecular biology·2024
Reduced dynamic complexity allows structure elucidation of an excited state of KRASG13D
Communications Biology·2023· 16 citedOpen Access
Insights into the Cross Talk between Effector and Allosteric Lobes of KRAS from Methyl Conformational Dynamics
Journal of the American Chemical Society·2022· 26 citedOpen Access
Solution structure and dynamics of the mitochondrial‐targeted <scp>GTPase</scp>‐activating protein <scp>(GAP) VopE</scp> by an integrated <scp>NMR</scp>/<scp>SAXS</scp> approach
Protein Science·2022· 2 citedOpen Access
Coordination of Di-Acetylated Histone Ligands by the ATAD2 Bromodomain
International Journal of Molecular Sciences·2021· 17 citedOpen Access
Coordination of di-acetylated histone ligands by the ATAD2 bromodomain
2021· 5 citedOpen Access
Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain
Journal of Medicinal Chemistry·2020· 21 citedOpen Access
The BRPF1 bromodomain is a molecular reader of di-acetyllysine
2020Open Access
Solution Structure Determination of Arabidopsis Thaliana RALF8 Illustrates the use of Cutting-Edge Software Developed at the National Magnetic Resonance Facility at Madison
Biophysical Journal·2020Open Access
Designing cyclic competence-stimulating peptide (CSP) analogs with pan-group quorum-sensing inhibition activity in <i>Streptococcus pneumoniae</i>
Proceedings of the National Academy of Sciences·2020· 43 citedOpen Access
The BRPF1 bromodomain is a molecular reader of di-acetyllysine
Current Research in Structural Biology·2020· 21 citedOpen Access
Conformational Switch to a β-Turn in a Staphylococcal Quorum Sensing Signal Peptide Causes a Dramatic Increase in Potency
Journal of the American Chemical Society·2019· 19 citedOpen Access
Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70
PLoS ONE·2019· 15 citedOpen Access
Function and solution structure of the <scp><i>Arabidopsis thaliana</i></scp> RALF8 peptide
Protein Science·2019· 20 citedOpen Access
CSP1_DPC
Open MIND·2019
Conformational flexibility in the enterovirus RNA replication platform
RNA·2018· 11 citedOpen Access
Robust nomenclature and software for enhanced reproducibility in molecular modeling of small molecules
2018· 4 citedOpen Access
Structural Characterization of Competence-Stimulating Peptide Analogues Reveals Key Features for ComD1 and ComD2 Receptor Binding in <i>Streptococcus pneumoniae</i>
Biochemistry·2018· 22 citedOpen Access
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Frequent Co-authors

John L. Markley(18), Claudia C. Cornilescu(14), Ad Bax(10), Marco Tonelli(9), Yftah Tal‐Gan(7), Helen E. Blackwell(6), Samuel E. Butcher(5), Andrew T. Ulijasz(5), Richard D. Vierstra(5), Monika Ivancic(4), Woonghee Lee(4), Karen C. Glass(4), G. Marius Clore(3), Junrui Zhang(3), Yang Tian(3), Samuel Carlson(3), Srisathiyanarayanan Dharmaiah(3), Troy Taylor(3), Dominic Esposito(3), Dwight V. Nissley(3)