Patrick McKiernan

Birmingham Women’s and Children’s NHS Foundation Trust — United Kingdom

Medicine · Health Sciences

52h-index8.9kcitations279works1.32yr avg
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Research Topics

Liver Disease and Transplantation(71), Organ Transplantation Techniques and Outcomes(65), Metabolism and Genetic Disorders(65), Pediatric Hepatobiliary Diseases and Treatments(61), Liver Disease Diagnosis and Treatment(58)

Publications276 total

Refractory autoimmune hepatitis in children: Considerations for assessment and management
World Journal of Hepatology·2025Open Access
Reply to: “Comment on opinion paper on the diagnosis and treatment of progressive familial intrahepatic cholestasis”
JHEP Reports·2025· 2 citedOpen Access
Erratum to “Opinion paper on the diagnosis and treatment of progressive familial intrahepatic cholestasis” [JHEP Reports 6 (2024) 100949]
JHEP Reports·2024Open Access
Impact of citrulline substitution on clinical outcome after liver transplantation in carbamoyl phosphate synthetase 1 and ornithine transcarbamylase deficiency
Journal of Inherited Metabolic Disease·2024· 3 citedOpen Access
Genetic landscape of pediatric acute liver failure of indeterminate origin
Hepatology·2023· 26 citedOpen Access
Opinion paper on the diagnosis and treatment of progressive familial intrahepatic cholestasis
JHEP Reports·2023· 19 citedOpen Access
Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis
JHEP Reports·2023· 28 citedOpen Access
Validation of a Clinical Risk-based Classification System in a Large Nonalcoholic Fatty Liver Disease Real-world Cohort
Clinical Gastroenterology and Hepatology·2023· 16 cited
The role of immunosuppression in long-term graft hepatitis and fibrosis after paediatric liver transplant – comparison of two treatment protocols
Frontiers in Transplantation·2023· 1 citedOpen Access
Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency
JHEP Reports·2022· 18 citedOpen Access
Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy
Hepatology·2022· 39 citedOpen Access
Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease
Hepatology·2022· 23 citedOpen Access
Efficacy and safety of odevixibat over 72 weeks of treatment in patients with progressive familial intrahepatic cholestasis
Journal of Hepatology·2022· 1 cited
Analysis of quality of life, hepatic biochemical markers, and sleep in patients with progressive familial intrahepatic cholestasis who had a pruritus response with odevixibat treatment
Journal of Hepatology·2022· 1 cited
Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial
˜The œLancet. Gastroenterology & hepatology·2022· 157 citedOpen Access
EP1232: ODEVIXIBAT EFFECTS ON CHOLESTASIS-RELATED PARAMETERS: ANALYSIS OF POOLED DATA FROM THE PEDFIC 1 AND PEDFIC 2 STUDIES IN CHILDREN WITH PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS
Gastroenterology·2022
L3 Effects on serum bile acids, pruritus, and safety with up to 72 weeks of odevixibat treatment: pooled data from the PEDFIC 1 and PEDFIC 2 studies in children with progressive familial intrahepatic cholestasis
2022
O12 Hepatic parameters, growth, and sleep with responders and nonresponders to odevixibat treatment: pooled data from the PEDFIC 1 and PEDFIC 2 studies in children with progressive familial intrahepatic cholestasis
2022
Variation in Alanine Aminotransferase in Children with Non-Alcoholic Fatty Liver Disease
Children·2022· 6 citedOpen Access
Acute Liver Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference
Zurich Open Repository and Archive (University of Zurich)·2022· 8 citedOpen Access
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Frequent Co-authors

Déirdre Kelly(17), Jean de Ville de Goyet(6), Ulrich Baumann(4), Florence Lacaille(4), Hanna Mandel(4), Carlo Dionisi‐Vici(4), Robert H. Squires(4), Jerry Vockley(4), Sue V. Beath(4), Paul Gissen(3), Roderick H.J. Houwen(3), Stefan G. Hübscher(3), Corinne De Laet(3), René Santer(3), Elke Lainka(3), Benjamin L. Shneider(3), George Mazariegos(3), Peter Freisinger(3), Christian Staufner(3), Stefan Kölker(3)