David N. Church

Centre for Human Genetics — United Kingdom

Medicine · Health Sciences

45h-index9.2kcitations244works11.52yr avg
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Research Topics

Genetic factors in colorectal cancer(72), Cancer Genomics and Diagnostics(59), Cancer Immunotherapy and Biomarkers(42), Endometrial and Cervical Cancer Treatments(40), Colorectal Cancer Treatments and Studies(40)

Publications240 total

Supplementary Figure S1 from Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
2025Open Access
Supplementary Figure S4 from Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
2025Open Access
Supplementary Figure S5 from Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
2025Open Access
Supplementary Table 1 from Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
2025Open Access
Supplementary Figure S3 from Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
2025Open Access
Supplementary Table 2 from Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
2025Open Access
Supplementary Figure S2 from Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
2025Open Access
Data from Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
2025Open Access
Spatiotemporal Immune Landscape and Long-term Immune Memory in POLE-Mutant Endometrial Cancer at the Single-Cell Level
Cancer Immunology Research·2025· 1 cited
Replication-associated mechanisms contribute to an increased CpG > TpG mutation burden in mismatch repair-deficient cancers
Genome Medicine·2025Open Access
Abstract P5-04-24: ATV-1601 is a Potent and Selective Allosteric Inhibitor of AKT1E17K and Shows Profound and Durable Regressions in AKT1E17K-Driven Patient Derived Xenograft Models
Clinical Cancer Research·2025
Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction
2025Open Access
Activin A affects colorectal cancer progression and immunomodulation in a stage dependent manner
Scientific Reports·2025· 1 citedOpen Access
1014 Histopathological Correlates of Chromosomally Unstable Endometrial and Ovarian Carcinomas
Laboratory Investigation·2025
1013 Progression from NSMP to p53-abnormal Endometrial Carcinoma: Introducing Class-Switching in the Molecular Classification
Laboratory Investigation·2025Open Access
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study
Nature Communications·2024· 20 citedOpen Access
Single-cell AI-based detection and prognostic and predictive value of DNA mismatch repair deficiency in colorectal cancer
Cell Reports Medicine·2024· 6 citedOpen Access
The genomic landscape of 2,023 colorectal cancers
Nature·2024· 123 citedOpen Access
24P Standardizing data collection in adjuvant colon cancer trials: A consensus project from the IDEA and ACCENT international consortia and national experts
Annals of Oncology·2024Open Access
Neoadjuvant immune checkpoint blockade in mismatch repair deficient endometrial cancer: An update on recurrence-free survival and correlative biomarkers.
Journal of Clinical Oncology·2024
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Frequent Co-authors

Tjalling Bosse(24), Ian Tomlinson(20), Remi A. Nout(15), Vincent T.H.B.M. Smit(14), Carien L. Creutzberg(14), Hans W. Nijman(13), Claire Palles(12), Enric Domingo(10), Marco de Bruyn(10), David Kerr(10), Rachel Kerr(9), Alexandra Léary(9), Inge C. van Gool(8), Melanie Powell(7), Emma J. Crosbie(7), Linda Mileshkin(7), Ellen Stelloo(6), Helen Mackay(6), Mark A. Glaire(6), Viktor H. Koelzer(6)