Jun Shirakawa

Gunma University — Japan

Medicine · Health Sciences

30h-index3.3kcitations148works0.72yr avg
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Research Topics

Pancreatic function and diabetes(76), Metabolism, Diabetes, and Cancer(47), Diabetes Treatment and Management(28), Diabetes and associated disorders(27), Liver Disease Diagnosis and Treatment(11)

Publications148 total

Characterization of extracellular and membrane potentials in imeglimin‐treated islets
Journal of Diabetes Investigation·2026Open Access
Imeglimin ameliorates MASLD by targeting PEN2 to activate AMPK pathway
Metabolism·2025· 1 cited
Gαs defines the fundamental coupling mechanism of insulin secretion
Journal of Diabetes Investigation·2025Open Access
The insulin/IGF receptor puzzle in pancreatic β-cell recovery: a missing link for diabetes therapy?
The Journal of Biochemistry·2025Open Access
The proton-sensing OGR1 receptor and hypoxia-inducible factors promote metal ion–induced inflammatory responses in coronary artery smooth muscle cells
Journal of Biological Chemistry·2025Open Access
<b>Regulatory roles of IGF2R in insulin secretion and adaptive β-cell proliferation</b>
2025Open Access
Regulatory Roles of IGF2R in Insulin Secretion and Adaptive β-Cell Proliferation
Diabetes·2025· 2 cited
<b>Regulatory roles of IGF2R in insulin secretion and adaptive β-cell proliferation</b>
2025Open Access
Imeglimin suppresses glucagon secretion and induces a loss of α cell identity
Cell Reports Medicine·2025· 2 citedOpen Access
<b>Adenylosuccinate mediates imeglimin-induced proliferative and </b><b>antiapoptotic</b><b> effects in β-cells</b>
2025Open Access
Adenylosuccinate Mediates Imeglimin-Induced Proliferative and Antiapoptotic Effects in β-Cells
Diabetes·2025· 1 cited
<b>Adenylosuccinate mediates imeglimin-induced proliferative and </b><b>antiapoptotic</b><b> effects in β-cells</b>
2025Open Access
High glucose burden disrupts the glucose responsiveness of human pancreatic beta cells encapsulated in alginate fibers during Long-Term culture
Gene·2025
1806-P: Functional Analysis of NUPR1 in Age-Associated Changes in β-Cell Proliferation and Apoptosis
Diabetes·2025
1827-P: Adenylosuccinate Mediates Imeglimin-Induced Proliferative and Antiapoptotic Effects in β-Cells
Diabetes·2025
Expression analysis and possible functional roles of semaphorin/plexin/CRMP families in mouse pancreatic islets
Scientific Reports·2025Open Access
The antitumor effects of metformin are potentially mediated through LPA receptor inhibition
Diabetes Research and Clinical Practice·2025Open Access
The matricellular protein Fibulin-5 regulates β-cell proliferation in an autocrine/paracrine manner
iScience·2025· 2 citedOpen Access
High Glucose Burden Disrupts the Glucose Responsiveness of Human Pancreatic Beta Cells Encapsulated in Alginate Fibers During Long-Term Culture
SSRN Electronic Journal·2025Open Access
Vagal sensory neuron-derived FGF3 controls insulin secretion
Developmental Cell·2024· 5 citedOpen Access
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Frequent Co-authors

Yasuo Terauchi(27), Yu Togashi(19), Rohit Kulkarni(16), Tomoko Okuyama(12), Kazuki Tajima(11), Kazuki Orime(11), Mayu Kyohara(11), Koichiro Sato(7), Dario F. De Jesus(6), Yuzuru Ito(5), Hideaki Inoue(5), Ryota Inoue(5), Mitsuyo Kaji(4), Abdelfattah El Ouaamari(4), Ercument Dirice(4), Chong Wee Liew(4), Tomozumi Takatani(4), Naoto Kubota(4), Takashi Kadowaki(4), Akinobu Nakamura(4)