Bared Safieh‐Garabedian

Qatar University — QA

Medicine · Health Sciences

29h-index4.6kcitations79works4.52yr avg
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Research Topics

Pain Mechanisms and Treatments(26), Neuropeptides and Animal Physiology(26), Stress Responses and Cortisol(13), Immune Response and Inflammation(12), Pharmacological Effects of Natural Compounds(7)

Publications79 total

Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Journal of Cellular Biochemistry·2024· 4 citedOpen Access
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
Biochemical Journal·2024· 5 citedOpen Access
Pyridoxine non-responsive p.R336C mutation alters the molecular properties of cystathionine beta-synthase leading to severe homocystinuria phenotype
Biochimica et Biophysica Acta (BBA) - General Subjects·2022· 13 citedOpen Access
Cerebrospinal α‐Synuclein Oligomers Reflect Disease Motor Severity in <scp>DeNoPa</scp> Longitudinal Cohort
Movement Disorders·2021· 42 citedOpen Access
Cerebrospinal Fluid α-Synuclein Species in Cognitive and Movements Disorders
Brain Sciences·2021· 32 citedOpen Access
Defective Interaction of Cam with RyR2 Cam-Binding Pocket Might Contribute to Arrhythmogenic Cardiac Disease
Biophysical Journal·2020Open Access
Essential Role of Sperm-Specific PLC-Zeta in Egg Activation and Male Factor Infertility: An Update
Frontiers in Cell and Developmental Biology·2020· 66 citedOpen Access
Arrhythmogenic calmodulin E105A mutation alters cardiac RyR2 regulation leading to cardiac dysfunction in zebrafish
Annals of the New York Academy of Sciences·2019· 13 cited
The Arrhythmogenic E105A CAM Mutation Dysregulates Normal Cardiac Function in Zebrafish by Altering CAM-Ca2+ and CAM-RyR2 Interactions
Biophysical Journal·2019Open Access
Targeting inflammatory components in neuropathic pain: The analgesic effect of thymulin related peptide
Neuroscience Letters·2018· 27 cited
Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction
Biochemical Journal·2018· 15 cited
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Biophysical Journal·2018· 2 citedOpen Access
Transcriptional expression of inflammatory mediators in various somatosensory relay centers in the brain of rat models of peripheral mononeuropathy and local inflammation
Journal of Neuroimmunology·2016· 14 cited
Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease
Molecular Neurodegeneration·2016· 279 citedOpen Access
Targeting α-synuclein as a therapeutic strategy for Parkinson’s disease
Expert Opinion on Therapeutic Targets·2015· 19 cited
Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils
Neurobiology of Disease·2014· 104 citedOpen Access
Involvement of the α7-nicotinic acetylcholine receptors in the anti-inflammatory action of the thymulin-related peptide (PAT)
Neuroscience·2013· 7 cited
Targeting neuroinflammation for therapeutic intervention in neurodegenerative pathologies: a role for the peptide analogue of thymulin (PAT)
Expert Opinion on Therapeutic Targets·2012· 10 cited
706 ATTENUATION OF VISCERAL PAIN IN RATS BY A SYNTHETIC PEPTIDE ANALOGUE TO THYMULIN (PAT)
European Journal of Pain·2009
Transient increase in cytokines and nerve growth factor in the rat dorsal root ganglia after nerve lesion and peripheral inflammation
Journal of Neuroimmunology·2009· 11 cited
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Frequent Co-authors

Nayef E. Saadé(33), Suhayl J. Jabbur(16), John J. Haddad(15), Salim A. Kanaan(10), Stephen Poole(8), Stephen C. Land(6), Samir Atweh(6), Clifford J. Woolf(5), Omar M. A. El‐Agnaf(5), Charbel Massaad(5), Michail Nomikos(4), Andrew Allchorne(3), Nour K. Majbour(3), Ryszard Lauterbach(3), Angelos Thanassoulas(3), Mireille Dardenne(3), Ghassan Mouneimne(3), Raffy H. Jalakhian(3), Mustafa T. Ardah(2), Takahiko Tokuda(2)