Yasushi Yamazoe

Tohoku University — Japan

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

57h-index11.5kcitations435works1.22yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(213), Drug Transport and Resistance Mechanisms(82), Carcinogens and Genotoxicity Assessment(45), Drug-Induced Hepatotoxicity and Protection(31), Computational Drug Discovery Methods(30)

Publications435 total

Construction of refined CYP2D6-Template system for studies of its metabolism and inhibition
Drug Metabolism and Pharmacokinetics·2025· 1 cited
The refined CYP2B6-Template system for studies of its ligand metabolisms
Drug Metabolism and Pharmacokinetics·2024· 3 cited
P05-40 Extracting hepatotoxicity-related insights through analysis on animal toxicity database – towards improving in silico prediction accuracy
Toxicology Letters·2024
Retraction Notice
Food Safety·2024Open Access
Construction of a CYP2J2-Template System and Its Application for Ligand Metabolism Prediction
Food Safety·2024· 2 citedOpen Access
Construction of a fused grid-based CYP2C18-Template system and its application to drug metabolism
Drug Metabolism and Pharmacokinetics·2023· 5 cited
Application of fused-grid-based CYP-Template systems for genotoxic substances to understand the metabolisms
Genes and Environment·2023· 6 citedOpen Access
Construction of a fused grid-based CYP2C8-Template system and the application
Drug Metabolism and Pharmacokinetics·2023· 5 cited
Construction of a fused grid-based CYP2C19-Template system and the application
Drug Metabolism and Pharmacokinetics·2022· 8 cited
Construction of a fused grid-based template system of CYP2C9 and its application
Drug Metabolism and Pharmacokinetics·2022· 11 cited
Application of CYP1A2-Template System to Understand Metabolic Processes in the Safety Assessment
Food Safety·2022· 10 citedOpen Access
Combined Risk Assessment of Food-derived Coumarin with <i>in Silico</i> Approaches
Food Safety·2022· 16 citedOpen Access
Refined CYP2E1∗ Template∗∗ system to decipher the ligand-interactions
Drug Metabolism and Pharmacokinetics·2021· 11 cited
Subject fields in Food Safety during 10 years
Food Safety·2021· 1 citedOpen Access
Deciphering Key Interactions of Ligands with CYP3A4-Template* system
Food Safety·2021· 11 citedOpen Access
Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template
Drug Metabolism and Pharmacokinetics·2020· 13 cited
Antiepileptic Drug–Activated Constitutive Androstane Receptor Inhibits Peroxisome Proliferator–Activated Receptor α and Peroxisome Proliferator–Activated Receptor γ Coactivator 1α–Dependent Gene Expression to Increase Blood Triglyceride Levels
Molecular Pharmacology·2020· 12 cited
Applications of a grid-based CYP3A4 Template system to understand the interacting mechanisms of large-size ligands; part 4 of CYP3A4 Template study
Drug Metabolism and Pharmacokinetics·2020· 8 cited
Versatile applicability of a grid-based CYP3A4 Template to understand the interacting mechanisms with the small-size ligands; part 3 of CYP3A4 Template study
Drug Metabolism and Pharmacokinetics·2020· 13 cited
Prediction and Characterization of CYP3A4-mediated Metabolisms of Azole Fungicides: an Application of the Fused-grid Template* system
Food Safety·2020· 17 citedOpen Access
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Frequent Co-authors

Kiyoshi Nagata(16), Ryuichi Kato(10), Tetsuya Kamataki(8), Masaaki Miyata(7), Kouichi Yoshinari(6), Katsuyuki Fukuda(5), Norie Murayama(5), Miki Shimada(5), Lian‐Qing Guo(4), Tomihisa Ohta(4), Frank J. Gonzalez(4), Masayuki Shimada(3), Ryuji Kato(3), Tsutomu Matsubara(3), Kenji Ishii(3), Ryuichi Kato(3), Shogo Ozawa(3), Fred F. Kadlubar(3), Noriko Ohashi(2), Masayoshi Yoshikawa(2)