Sylvain Provot

Inserm — France

Medicine · Health Sciences

20h-index2.5kcitations54works0.02yr avg
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Research Topics

Osteoarthritis Treatment and Mechanisms(8), Cancer, Hypoxia, and Metabolism(8), Bone health and treatments(8), Bone Metabolism and Diseases(7), Cancer-related molecular mechanisms research(5)

Publications51 total

Hypoxia signaling pathway activation in osteoblasts suppresses osteocalcin production but does not alter male fertility in mice
European Journal of Endocrinology·2025
WHIM Syndrome-linked CXCR4 mutations drive osteoporosis
Nature Communications·2023· 14 citedOpen Access
Increased bone resorption in mice bearing WHIM Syndrome mutations does not rely on increased intrinsic OCL differentiation capacity
Bone Reports·2022Open Access
WHIM Syndrome-linked CXCR4 mutations drive osteoporosis by mitigating the osteogenic specification of skeletal stromal cells
Research Square (Research Square)·2022Open Access
Inhibition of sphingosine 1-phosphate protects mice against chondrocyte catabolism and osteoarthritis
Osteoarthritis and Cartilage·2021· 21 citedOpen Access
Development of the skeleton
Elsevier eBooks·2020
PTH-induced bone anabolism promotes systemic breast cancer growth and metastasis
Bone Reports·2020Open Access
In Memoriam: Zena Werb (1945–2020)
Journal of Bone and Mineral Research·2020Open Access
Zena Werb (1945–2020)
Cell stem cell·2020Open Access
Zena Werb (1945–2020)
Developmental Cell·2020Open Access
Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice
Nature Communications·2020· 213 citedOpen Access
Chronic circadian disruption modulates breast cancer cell stemness and their immune microenvironment to drive metastasis in mice
2019· 2 citedOpen Access
Murine platelet production is suppressed by S1P release in the hematopoietic niche, not facilitated by blood S1P sensing
Blood Advances·2019· 20 citedOpen Access
PiT1/Slc20a1 Is Required for Endoplasmic Reticulum Homeostasis, Chondrocyte Survival, and Skeletal Development
Journal of Bone and Mineral Research·2018· 35 cited
Calpain-6 controls the fate of sarcoma stem cells by promoting autophagy and preventing senescence
JCI Insight·2018· 27 citedOpen Access
The systemic control of cancers by the osteoblasts
Oncoscience·2018· 1 citedOpen Access
Signaling Pathways Underlying Bone Metastasis: Hypoxia Signaling in Bone Metastasis and Beyond
Current Molecular Biology Reports·2018· 3 cited
HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice
Proceedings of the National Academy of Sciences·2018· 92 citedOpen Access
La signalisation HIF dans les ostéoprogéniteurs stimule la croissance et la dissémination des tumeurs mammaires
Revue du Rhumatisme·2016
Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice
Proceedings of the National Academy of Sciences·2016· 120 citedOpen Access
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Frequent Co-authors

Claire-Sophie Devignes(11), Ernestina Schipani(9), Henry M. Kronenberg(9), Martine Cohen‐Solal(9), Yetki Aslan(8), Zena Werb(7), Eric Haÿ(6), Jonathan Chou(5), Dominique Modrowski(5), Hang‐Korng Ea(5), Georges Calothy(5), Audrey Brenot(4), W. Bouaziz(4), Johanna Sigaux(4), Amy-Jo Casbon(4), Marie‐Paule Felder‐Schmittbuhl(4), Joy Y. Wu(4), Lea Hanna Doumit Sakr(4), Caroline Marty(4), Audrey Devillers(3)