Carlos Roberto Alves

Fundação Oswaldo Cruz — Brazil

Medicine · Health Sciences

28h-index2.7kcitations121works3.42yr avg
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Research Topics

Research on Leishmaniasis Studies(81), Trypanosoma species research and implications(47), Synthesis and Biological Evaluation(14), Insect Pest Control Strategies(12), Bioactive Compounds and Antitumor Agents(12)

Publications121 total

Histopathological analysis reveals mild to moderate changes in BALB/c mice after short-term administration of a microemulsion loaded with epoxy-α-lapachone
Experimental and Molecular Pathology·2025Open Access
Molecular and biochemical approaches of the trypanothione system in Leishmania spp.: A key player in parasite resistance to antimonial therapy
Biochimie·2025· 1 cited
Leishmania (Viannia) braziliensis Thor strain and subpopulations Thor03, Thor10, and Thor22 have differences in the surface membrane proteases activity profile
Biochimie·2025· 2 cited
A Virtual Screening Approach to Evaluate the Multitarget Potential of a Chalcone Library with Binding Properties to Oligopeptidase B and Cysteine Proteinase B from Leishmania (Viannia) braziliensis
International Journal of Molecular Sciences·2025· 4 citedOpen Access
Exploring the binomial BALB/c-Leishmania (Viannia) braziliensis model to assess the in vivo performance of Thor strain subpopulations
Experimental Parasitology·2024· 3 cited
Generation and characterization of a monoclonal antibody Fab fragment targeting PBP2a in methicillin-resistant Staphylococcus aureus
Journal of Immunological Methods·2024· 2 cited
Evidence of Hyperglycemic Levels Improving the Binding Capacity between Human Serum Albumin and the Antihypertensive Drug Hydrochlorothiazide
Scientia Pharmaceutica·2024· 13 citedOpen Access
Efficacy of the treatment using a microemulsion loaded with epoxy-α-lapachone in combination with meglumine antimoniate against murine infection by Leishmania (Leishmania) amazonensis
International Journal for Parasitology Drugs and Drug Resistance·2024· 4 citedOpen Access
Assessing proteases and enzymes of the trypanothione system in subpopulations of Leishmania (Viannia) braziliensis Thor strain during macrophage infection.
PubMed·2024· 3 citedOpen Access
Epoxy-a-lapachone in nanosystem: a prototype drug for leishmaniasis assessed in the binomial BALB/c - Leishmania (Leishmania) amazonensis
Memórias do Instituto Oswaldo Cruz·2024· 2 citedOpen Access
Evidence of Guanidines Potential against Leishmania (Viannia) braziliensis: Exploring In Vitro Effectiveness, Toxicities and of Innate Immunity Response Effects
Biomolecules·2023· 7 citedOpen Access
Recent advances in surface plasmon resonance as a powerful approach for studying Leishmania spp. and Trypanosoma cruzi parasites
Talanta Open·2023· 6 citedOpen Access
Degron Pathways and Leishmaniasis: Debating Potential Roles of Leishmania spp. Proteases Activity on Guiding Hosts Immune Response and Their Relevance to the Development of Vaccines
Vaccines·2023· 4 citedOpen Access
Assessing nystatin cream treatment efficacy against Leishmania (L.) amazonensis infection in BALB/c model
Experimental Parasitology·2023· 3 cited
A New Strategy for Mapping Epitopes of LACK and PEPCK Proteins of Leishmania amazonensis Specific for Major Histocompatibility Complex Class I
International Journal of Molecular Sciences·2023· 5 citedOpen Access
Development of a microemulsion loaded with epoxy-α-lapachone against Leishmania (Leishmania) amazonensis murine infection
International Journal of Pharmaceutics·2023· 9 cited
Epoxy-α-lapachone (2,2-Dimethyl-3,4-dihydro-spiro[2H-naphtho[2,3-b]pyran-10,2′-oxirane]-5(10H)-one): a promising molecule to control infections caused by protozoan parasites
The Brazilian Journal of Infectious Diseases·2023· 4 citedOpen Access
Assessing the effect of antimony pressure on trypanothione reductase activity in Leishmania (Viannia) braziliensis
Biochimie·2022· 7 cited
Impact of collaborative actions of <i>Leishmania (Viannia) braziliensis</i> subpopulations on the infection profile
Parasitology·2022· 7 citedOpen Access
Novel Insights Into Leishmania (Viannia) braziliensis In Vitro Fitness Guided by Temperature Changes Along With Its Subtilisins and Oligopeptidase B
Frontiers in Cellular and Infection Microbiology·2022· 9 citedOpen Access
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Frequent Co-authors

Franklin Souza‐Silva(20), Bernardo Acácio Santini Pereira(13), Mirian Cláudia de Souza Pereira(11), Saulo Cabral Bourguignon(9), Salvatore G. De-Simone(8), Luzia Monteiro de Castro Côrtes(8), Rosa T. Pinho(7), Léa Cysne‐Finkelstein(6), Francisco Odêncio Rodrigues de Oliveira(6), Constança Britto(5), Vı́tor F. Ferreira(5), Reginaldo Peçanha Brazil(4), Álvaro Luiz Bertho(4), Natalia Fintelman‐Rodrigues(4), Carolina Q. Sacramento(4), Suelen da Silva Gomes Dias(4), Nicolas Carels(4), Mariana Silva-Almeida(4), Guilherme C. Lechuga(4), Leny Toma(4)