John M. Kelly

University of London — United Kingdom

Medicine · Health Sciences

53h-index7.6kcitations220works1.52yr avg
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Research Topics

Trypanosoma species research and implications(172), Research on Leishmaniasis Studies(121), Synthesis and Biological Evaluation(47), Biochemical and Molecular Research(21), Parasites and Host Interactions(12)

Publications220 total

Synthesis and evaluation of nitroheterocyclic aromatic adamantane amides with trypanocidal activity. Part II
RSC Medicinal Chemistry·2025Open Access
A Rapid Method for Purifying Intact Trypanosoma cruzi Amastigotes from Host Cells, In Vitro and In Vivo, for Downstream ‘Omic Analysis
Methods in molecular biology·2025· 1 citedOpen Access
Surgical Implantation of a Wireless System for Portal Vein Pressure Monitoring in a Chronic Fontan Ovine Model
Journal of Visualized Experiments·2025
Transcriptomic and proteomic analysis of quiescent epimastigotes as a resource for investigating <i>Trypanosoma cruzi</i> persistence
2025Open Access
Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP
Nature Communications·2025· 1 citedOpen Access
Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease
Science Translational Medicine·2025· 2 citedOpen Access
Syntheses of benzothiazole amidoximes and arylimidamides and evaluation of their ADME and DNA binding properties and activity against Trypanosoma brucei
European Journal of Medicinal Chemistry·2025
Stage-specific MCM protein expression in Trypanosoma cruzi: insights into metacyclogenesis and G1 arrested epimastigotes
Frontiers in Cellular and Infection Microbiology·2025· 2 citedOpen Access
Pharmacokinetic-pharmacodynamic modeling of benznidazole and its antitrypanosomal activity in a murine model of chronic Chagas disease
PLoS neglected tropical diseases·2025· 2 citedOpen Access
Intermittent suppressive posaconazole therapy is ineffective at mitigating cardiac and digestive tract pathologies in an experimental model of chronic Chagas disease
Antimicrobial Agents and Chemotherapy·2025· 1 citedOpen Access
Statins do not reduce the parasite burden during experimental <i>Trypanosoma cruzi</i> infection
Antimicrobial Agents and Chemotherapy·2025Open Access
Stage-Specific MCM Protein Expression in <i>Trypanosoma cruzi</i> : Insights Into Metacyclogenesis and G1 Arrested epimastigotes
2025Open Access
Statins do not reduce the parasite burden during experimental <i>Trypanosoma cruzi</i> infection
2025Open Access
Synthesis and Evaluation of the Antitrypanosomal Activity, Adme and DNA Binding Properties of Benzothiazoleamidoximes and Arylimidamides
SSRN Electronic Journal·2025Open Access
New <i>Trypanosoma brucei</i> acting derivatives incorporating 1-(4-phenyl)adamantane and 1-(4-phenoxyphenyl)adamantane
RSC Medicinal Chemistry·2025Open Access
Intermittent suppressive posaconazole therapy is ineffective at mitigating cardiac and digestive tract pathologies in an experimental model of chronic Chagas disease
2024Open Access
Animal models for exploring Chagas disease pathogenesis and supporting drug discovery
Clinical Microbiology Reviews·2024· 4 citedOpen Access
Dynamics of Trypanosoma cruzi infection in hamsters and novel association with progressive motor dysfunction
PLoS neglected tropical diseases·2024· 2 citedOpen Access
New Lipophilic Hydroxamates as Promising Trypanocidal Agents: Design, Synthesis, SAR, and Conformational Behavior Studies
ACS Medicinal Chemistry Letters·2024· 1 citedOpen Access
A panel of phenotypically and genotypically diverse bioluminescent:fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research
PLoS neglected tropical diseases·2024· 7 citedOpen Access
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Frequent Co-authors

Martin C. Taylor(24), Shane R. Wilkinson(16), Michael D. Lewis(12), Amanda Fortes Francisco(10), Shiromani Jayawardhana(7), Michael A. Miles(6), David Horn(5), David A. Baker(4), S. Radhika Prathalingam(4), David J. Meyer(3), Samson O. Obado(3), D.K. Muhia(3), Hollie Burrell‐Saward(2), Alex P. McLatchie(2), Belinda S. Hall(2), Elizabeth V. Bromley(2), Isabel Maurício(2), Eric Chatelain(2), Lucı́a Piacenza(2), María Noel Álvarez(2)