Klaus Groschner

Medical University of Graz — Austria

Neuroscience · Life Sciences

50h-index7.7kcitations231works2.82yr avg
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Research Topics

Ion Channels and Receptors(127), Ion channel regulation and function(76), Neurobiology and Insect Physiology Research(46), Cardiac electrophysiology and arrhythmias(37), Nitric Oxide and Endothelin Effects(21)

Publications231 total

Utilizing native nanodiscs to isolate active TRPC3 channels and expand structural analysis capabilities
Scientific Reports·2025· 1 citedOpen Access
Photopharmacology reveals high-specificity linkage of Ca2+ entry at TRPC6 nanodomains to NFAT activation in mast cells
Frontiers in Immunology·2025· 1 citedOpen Access
Targeting TRPC channels for control of arthritis-induced bone erosion
Science Advances·2025· 2 citedOpen Access
Investigating TRP Channel Function with Tools for High-Precision Manipulation of Gating Mechanism by Light
2024
TRPC1: The housekeeper of the hippocampus
Cell Calcium·2024· 5 citedOpen Access
PIP2 modulates TRPC3 activity via TRP helix and S4-S5 linker
Nature Communications·2024· 11 citedOpen Access
Deciphering the mechanism of cholesterol sensing in TRPC3 through photopharmacology
Biophysical Journal·2024· 1 citedOpen Access
Bidirectional Allosteric Coupling between PIP2 Binding and the Pore of the Oncochannel TRPV6
International Journal of Molecular Sciences·2024· 1 citedOpen Access
Coordinating the regulatory dance: how PIP2 modulates TRPC3 activity via TRP helix and S4-S5 linker
2023· 1 citedOpen Access
Nanojunctions: Specificity of Ca2+ signaling requires nano-scale architecture of intracellular membrane contact sites
Cell Calcium·2023· 2 citedOpen Access
Calcium transport and sensing in TRPC channels – New insights into a complex feedback regulation
Cell Calcium·2023· 9 cited
Arriving at the next level of complexity in IP3R and SOCE signaling
Cell Calcium·2023· 1 cited
Nanojunctions: Specificity of Ca <sup>2+</sup> signalling requires nano-scale architecture of intracellular membrane contact sites
2023Open Access
Photopharmacological dissociation of transcriptional activation and degranulation of mast cells
Biophysical Journal·2023Open Access
Dynamic communication between TRPC3 and IP3R shape Ca2+ signaling signatures
Biophysical Journal·2023Open Access
TRPC3 Regulates Islet Beta‐Cell Insulin Secretion
Advanced Science·2023· 13 citedOpen Access
TRPC3 governs the spatiotemporal organization of cellular Ca2+ signatures by functional coupling to IP3 receptors
Cell Calcium·2022· 11 citedOpen Access
Differences in circulating obesity-related microRNAs in Austrian and Japanese men: A two-country cohort analysis
Metabolism Open·2022· 4 citedOpen Access
TRPC3 interaction with cholesterol as explored through MD (raw data)
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
TRPC3 interaction with cholesterol as explored through MD (raw data)
Biomolecules·2022Open Access
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Frequent Co-authors

Christoph Romanin(29), Rainer Schindl(15), Martin Muik(14), Isabella Derler(14), Irene Frischauf(11), Marc Fahrner(9), Michael Poteser(9), Wolfgang F. Graier(7), Judith Bergsmann(6), Petra Eder(5), Reinhard Fritsch(5), Heike Kahr(5), Barbara Lackner(5), Annarita Graziani(5), Christian Rosker(5), Michael X. Zhu(4), Wolfgang Schreibmayer(4), W. R. Kukovetz(4), Bernhard Doleschal(3), Michaela Lichtenegger(3)