Florian Sonntag

Medigene (Germany) — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index1.2kcitations12works2.32yr avg
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Research Topics

Virus-based gene therapy research(10), Bacteriophages and microbial interactions(4), Virology and Viral Diseases(3), Animal Virus Infections Studies(2), Viral Infectious Diseases and Gene Expression in Insects(2)

Publications12 total

A human genome wide screen identifies miRNAs to increase recombinant Adeno-associated virus production in HEK293 cells
New Biotechnology·2025Open Access
Recombinant AAV batch profiling by nanopore sequencing elucidates product-related DNA impurities and vector genome length distribution
Molecular Therapy — Methods & Clinical Development·2025· 4 citedOpen Access
Polo-like kinase inhibitors increase AAV production by halting cell cycle progression
Molecular Therapy — Methods & Clinical Development·2025· 3 citedOpen Access
Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate
Blood·2019
Evaluation of life cycle defective adenovirus mutants for production of adeno‐associated virus vectors
The Journal of Gene Medicine·2019· 5 cited
The SUMOylation Pathway Restricts Gene Transduction by Adeno-Associated Viruses
PLoS Pathogens·2015· 33 citedOpen Access
Properties of the Adeno-Associated Virus Assembly-Activating Protein
Journal of Virology·2012· 96 citedOpen Access
Nuclear translocation of adeno-associated virus type 2 capsid proteins for virion assembly
Journal of General Virology·2012· 22 cited
The Assembly-Activating Protein Promotes Capsid Assembly of Different Adeno-Associated Virus Serotypes
Journal of Virology·2011· 178 citedOpen Access
A viral assembly factor promotes AAV2 capsid formation in the nucleolus
Proceedings of the National Academy of Sciences·2010· 386 citedOpen Access
Adeno-Associated Virus Type 2 Capsids with Externalized VP1/VP2 Trafficking Domains Are Generated prior to Passage through the Cytoplasm and Are Maintained until Uncoating Occurs in the Nucleus
Journal of Virology·2006· 267 citedOpen Access
Mutational Analysis of Narrow Pores at the Fivefold Symmetry Axes of Adeno-Associated Virus Type 2 Capsids Reveals a Dual Role in Genome Packaging and Activation of Phospholipase A2 Activity
Journal of Virology·2005· 195 citedOpen Access

Frequent Co-authors

Jürgen A. Kleinschmidt(7), Markus Hörer(5), Kristin Schmidt(3), Andreas Schulze(3), Svenja Bleker(2), Karen Nieto(2), Ruth Popa-Wagner(2), Barbara Leuchs(1), Roger Fischer(1), Katharina Köther(1), Katja Schmidt(1), Margit Weghofer(1), Christina Raupp(1), Andrea Kuck(1), Britta Gerlach(1), Bettina Böttcher(1), Oliver J. Müller(1), Kerstin Lux(1), Matthias Naumer(1), Christian Panke(1)