África Vales

Universidad de Navarra — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index702citations56works3.62yr avg
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Research Topics

Virus-based gene therapy research(19), Hepatitis B Virus Studies(18), Hepatitis C virus research(17), Influenza Virus Research Studies(8), Hepatitis Viruses Studies and Epidemiology(7)

Publications56 total

Inhibition of T cell infiltration and soluble TNF signaling is neuroprotective in the alpha-synuclein overexpressing mouse model of Parkinson’s disease
npj Parkinson s Disease·2025· 2 citedOpen Access
Loss of PLA2G4E compromises synaptic structure and cognitive outcomes in mice
Life Science Alliance·2025· 1 citedOpen Access
Inhibition of T cell infiltration and soluble TNF signaling is neuroprotective in the alpha-synuclein overexpressing mouse model of Parkinson’s disease
2025Open Access
Protective role of RIPK1 scaffolding against HDV-induced hepatocyte cell death and the significance of cytokines in mice
PLoS Pathogens·2024Open Access
Deciphering the Role of Post-Translational Modifications and Cellular Location of Hepatitis Delta Virus (HDV) Antigens in HDV-Mediated Liver Damage in Mice
Viruses·2024· 1 citedOpen Access
Deciphering the Role of Post-translational Modifications and Cellular Location of HDV Antigens in HDV-Mediated Liver Damage in Mice
Preprints.org·2024· 1 citedOpen Access
Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1
EMBO Molecular Medicine·2024· 20 citedOpen Access
Protective Role of RIPK1 Scaffolding against HDV-Induced Hepatocyte cell death and the Significance of Cytokines in Mice
2023Open Access
Topoisomerase Inhibitors Increase Episomal DNA Expression by Inducing the Integration of Episomal DNA in Hepatic Cells
Pharmaceutics·2023· 1 citedOpen Access
IDENTIFYING ALPHA-SYNUCLEIN INTERACTOME MAP IN A MOUSE MODEL USING PROXIMITY-BIOTINILATION.
IBRO Neuroscience Reports·2023Open Access
Cardiac Progenitor Cell Exosomal miR-935 Protects against Oxidative Stress
Cells·2023· 11 citedOpen Access
Stabilization of 14-3-3 protein-protein interactions with Fusicoccin-A decreases alpha-synuclein dependent cell-autonomous death in neuronal and mouse models
Neurobiology of Disease·2023· 11 citedOpen Access
Microglia and astrocyte activation is region‐dependent in the α‐synuclein mouse model of Parkinson's disease
Glia·2022· 65 citedOpen Access
AAV-HDV: An Attractive Platform for the In Vivo Study of HDV Biology and the Mechanism of Disease Pathogenesis
Viruses·2021· 9 citedOpen Access
AAV-HDV an Attractive Platform for the In Vivo Study of HDV Biology and Mechanism of Disease Pathogenesis
Preprints.org·2021· 5 citedOpen Access
TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection
JHEP Reports·2020· 24 citedOpen Access
Danio Rerio as Model Organism for Adenoviral Vector Evaluation
Genes·2019· 11 citedOpen Access
Effect of heart ischemia and administration route on biodistribution and transduction efficiency of AAV9 vectors
Journal of Tissue Engineering and Regenerative Medicine·2019· 22 cited
CRISPR/Cas9-mediated glycolate oxidase disruption is an efficacious and safe treatment for primary hyperoxaluria type I
Nature Communications·2018· 82 citedOpen Access
Erratum to “A new HDV mouse model identifies mitochondrial antiviral signaling protein (MAVS) as a key player in IFN-β induction” [J Hepatol 67 (2017) 669–679]
Journal of Hepatology·2018· 1 citedOpen Access
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Frequent Co-authors

Gloria González‐Aseguinolaza(43), Jesús Prìeto(26), Cristina Olagüe(25), Marianna Di Scala(13), Pedro Berraondo(13), Juan Ruiz(8), Rafael Aldabe(8), Juan José Lasarte(7), Carla Usai(7), Lucía Vanrell(7), Julien Crettaz(7), Laura Ochoa‐Callejero(7), Sandra Hervás‐Stubbs(6), Marta Aymerich(5), Mirja Hommel(5), Sheila Maestro(5), Gracián Camps(5), Itziar Otano(5), Eduardo Salido(4), Leyre Basurco(4)