Daniele D’Ambrosio

Actelion (Switzerland) — Switzerland

Immunology and Microbiology · Life Sciences

43h-index11.2kcitations108works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(35), Chemokine receptors and signaling(28), Immunotherapy and Immune Responses(26), Immune Cell Function and Interaction(20), Sphingolipid Metabolism and Signaling(12)

Publications108 total

Ponesimod as add-on treatment in patients with active relapsing multiple sclerosis under dimethyl fumarate (POINT): A phase 3, randomized, placebo-controlled clinical trial
Multiple Sclerosis and Related Disorders·2025
Results of an observational retrospective multicenter study: “Campania INternal medicine - the Clinical INternist for heart failure”
Italian Journal of Medicine·2023Open Access
Robocasting of multicomponent sol-gel–derived silicate bioactive glass scaffolds for bone tissue engineering
Ceramics International·2022· 13 cited
Acute Renal Infarction: a Diagnostic Challenge
ICUS and Nursing Web Journal·2021
Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study
JAMA Neurology·2021· 203 citedOpen Access
Efficacy and Safety of 2 Doses of Ponesimod (10 and 20 mg o.d.): Interim Analysis of a Phase II Extension Trial in Relapsing-remitting Multiple Sclerosis (P3.398)
Neurology·2018· 2 cited
Modeling clinical efficacy of the S1P receptor modulator ponesimod in psoriasis
Journal of Dermatological Science·2017· 14 cited
Effects of multiple-dose ponesimod, a selective S1P1 receptor modulator, on lymphocyte subsets in healthy humans
SHILAP Revista de lepidopterología·2016· 1 citedOpen Access
Effects of multiple-dose ponesimod, a selective S1P<sub>1</sub> receptor modulator, on lymphocyte subsets in healthy humans
Drug Design Development and Therapy·2016· 15 citedOpen Access
Ponesimod, a selective S1P1 receptor modulator: a potential treatment for multiple sclerosis and other immune-mediated diseases
Therapeutic Advances in Chronic Disease·2016· 100 citedOpen Access
Biocomparison of THREE formulations of the S1P1 receptor modulator ponesimod in healthy subjects
Clinical Therapeutics·2015
Does comprehensive geriatric assessment improve the estimate of surgical risk in elderly patients? An Italian multicenter observational study
The American Journal of Surgery·2015· 33 cited
Biocomparison of Three Formulations of the S1P1 Receptor Modulator Ponesimod in Healthy Subjects
Drugs in R&D·2015· 8 citedOpen Access
Receptor Signal Transduction and Cytokine Gene Expression in T Lymphocytes
2015
Three different up-titration regimens of ponesimod, an S1P<sub>1</sub>receptor modulator, in healthy subjects
The Journal of Clinical Pharmacology·2015· 20 cited
Differential effects of ponesimod, a selective S1P<sub>1</sub>receptor modulator, on blood-circulating human T cell subpopulations
Immunopharmacology and Immunotoxicology·2014· 22 cited
Oral ponesimod in patients with chronic plaque psoriasis: a randomised, double-blind, placebo-controlled phase 2 trial
The Lancet·2014· 144 cited
Clinical pharmacology of ponesimod, a selective S1P1 receptor modulator, after uptitration to supratherapeutic doses in healthy subjects
European Journal of Pharmaceutical Sciences·2014· 28 cited
Population pharmacokinetics and pharmacodynamics of ponesimod, a selective S1P1 receptor modulator
Journal of Pharmacokinetics and Pharmacodynamics·2014· 24 cited
Evans Syndrome Presented with Marginal Zone Lymphoma and Duodenal Neuroendocrine Tumor in an Elderly Woman
International journal of gerontology·2014· 2 citedOpen Access
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Frequent Co-authors

Francesco Sinigaglia(24), Paola Panina‐Bordignon(9), Andrea Iellem(9), Lucia Colantonio(8), Alberto Mantovani(7), Angela Santoni(7), Rosmarie Lang(6), Silvano Sozzani(6), Daniela Mazzeo(6), John C. Cambier(5), Lars Rogge(4), Francesco Cacciatore(4), Pasquale Abete(4), Raffaella Bonecchi(3), Giuseppe Bianchi(3), Paola Allavena(3), Margherita Mariani(3), Helios Recalde(3), Keli L. Hippen(3), Roberto Testi(3)