Saroj Gourkanti

University of California San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index475citations17works0.52yr avg
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Research Topics

RNA Research and Splicing(9), RNA modifications and cancer(8), RNA and protein synthesis mechanisms(5), Endoplasmic Reticulum Stress and Disease(4), Lipid Membrane Structure and Behavior(3)

Publications17 total

Rhomboid protease Rhbdl2 regulates macrophage recruitment and wound regeneration in zebrafish
2026Open Access
Holding Out for a Model: Rhomboid Superfamily in Vertebrate Development and Disease
Journal of Cellular Physiology·2025· 1 citedOpen Access
Derlin rhomboid pseudoproteases employ substrate engagement and lipid distortion to enable the retrotranslocation of ERAD membrane substrates
Cell Reports·2022· 3 citedOpen Access
Derlin rhomboid pseudoproteases employ substrate engagement and lipid distortion to enable the retrotranslocation of ERAD membrane substrates
Cell Reports·2021· 39 citedOpen Access
2007 – TRANSCRIPTIONAL CONTROL OF CBX5 BY THE RNA BINDING PROTEINS RBMX AND RBMXL1 MAINTAINS CHROMATIN STATE IN MYELOID LEUKEMIA
Experimental Hematology·2021· 1 cited
Transcriptional control of CBX5 by the RNA-binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia
Nature Cancer·2021· 31 citedOpen Access
Derlin rhomboid pseudoproteases employ substrate engagement and lipid distortion function for retrotranslocation of ER multi-spanning membrane substrates
2021· 3 citedOpen Access
Derlin Rhomboid Pseudoproteases Employ Substrate Engagement and Lipid Distortion Function for Retrotranslocation of ER Multi-Spanning Membrane Substrates
SSRN Electronic Journal·2021· 1 citedOpen Access
Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia
Blood·2020· 2 cited
HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells
Nature Communications·2020· 69 citedOpen Access
m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment
Cell Reports·2019· 163 citedOpen Access
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia
Nature Communications·2019· 144 citedOpen Access
The RNA Binding Protein MSI2 Has Increased RNA Binding Activity in Leukemic Stem Cells Compared to Normal Hematopoietic Stem Cells
Blood·2018· 1 cited
Small-Molecule Targeting of Musashi RNA-Binding Activity in Acute Myeloid Leukemia
Blood·2018· 1 cited
RNA Binding Protein Rbmx Is Required in Acute Myeloid Leukemia By Regulating the Transcriptional Activity of the Heterochromatin Protein HP1α
Blood·2018· 2 cited
m6A Maintains Hematopoietic Stem and Progenitor Cell Identity
Blood·2018
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia
2018· 14 citedOpen Access

Frequent Co-authors

Michael G. Kharas(11), Alexandra Schurer(10), Christina S. Leslie(8), Diu Nguyen(7), Ly Vu(7), Timothy Chou(7), Arthur Chow(6), James Taggart(6), Camila Prieto(6), Sonya E. Neal(5), Ersilia Barin(4), Anahita Nejatfard(4), Nicholas Wauer(4), Satarupa Bhaduri(4), Narinderbir Singh(4), Tiffany Kuo(4), Rachel Kandel(4), Rommie E. Amaro(4), Steven K. Albanese(3), Sun‐Mi Park(3)