Dirk Valckx

KU Leuven — Belgium

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index3.8kcitations29works0.02yr avg
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Research Topics

Diabetes and associated disorders(9), Pancreatic function and diabetes(7), Immune Cell Function and Interaction(6), Vitamin D Research Studies(5), Molecular Biology Techniques and Applications(5)

Publications28 total

Real-Time Polymerase Chain Reaction
Elsevier eBooks·2010· 6 cited
Increased peritoneal and endometrial gene expression of biologically relevant cytokines and growth factors during the menstrual phase in women with endometriosis
Fertility and Sterility·2006· 150 cited
Validation of real-time RT-PCR assays for mRNA quantification in baboons
Cytokine·2005· 26 cited
1α,25-Dihydroxyvitamin D3 restores thymocyte apoptosis sensitivity in non-obese diabetic (NOD) mice through dendritic cells
Journal of Autoimmunity·2005· 30 cited
Blocking IFN-gamma signaling cascade in islets alters their chemokine expression, but is insufficient for protection in vivo
Diabetologia·2005
Early Accumulation of Interferon-?? in Grafts Tolerized by Donor-Specific Blood Transfusion: Friend or Enemy?
Transplantation·2004· 9 cited
Regulation of 25-hydroxyvitamin d-1α-hydroxylase by IFNγ in human monocytic THP1 cells
The Journal of Steroid Biochemistry and Molecular Biology·2004· 18 cited
The use of real-time reverse transcriptase PCR for the quantification of cytokine gene expression.
PubMed·2003· 362 cited
Acute Shock Induced by Antigen Vaccination in NOD Mice
Diabetes·2003· 30 citedOpen Access
Inhibition of primary non-function and prolongation of graft survival of xenogeneic islets by non-steroidal anti-inflammatory agents in non-obese diabetic mice: correlation with diminished non-T-cell cytokines in the grafts and suppression of plasma nitrite production
Diabetologia·2002
An Overview of Real-Time Quantitative PCR: Applications to Quantify Cytokine Gene Expression
Methods·2001· 1.4k cited
In Vitro and In Vivo Analysis of the Immune System of Vitamin D Receptor Knockout Mice
Journal of Bone and Mineral Research·2001· 163 citedOpen Access
In vitro and in vivo analysis of the immune system of VDR-KO mice
2001· 1 cited
Early graft failure of xenogeneic islets in NOD mice is accompanied by high levels of interleukin-1 and low levels of transforming growth factor-beta mRNA in the grafts.
Diabetes·2000· 56 cited
1alpha,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543).
Diabetes·2000· 178 citedOpen Access
Identification and immune regulation of 25-hydroxyvitamin D-1-<i>α</i>-hydroxylase in murine macrophages
Clinical & Experimental Immunology·2000· 271 citedOpen Access
PRIMARY NONFUNCTION OF ISLET XENOGRAFTS IN SPONTANEOUSLY DIABETIC AUTOIMMUNE NOD MICE: CORRELATION WITH ELEVATED NON-T CELL CYTOKINES AND FASL EXPRESSION IN THE GRAFTS.
Transplantation·1999
QUANTIFICATION OF MURINE CYTOKINE mRNAs USING REAL TIME QUANTITATIVE REVERSE TRANSCRIPTASE PCR
Cytokine·1999· 561 cited
Novel alleles of yeast hexokinase PII with distinct effects on catalytic activity and catabolite repression of SUC2
Microbiology·1999· 80 cited
1,25-Dihydroxyvitamin D3 restores sensitivity to cyclophosphamide-induced apoptosis in non-obese diabetic (NOD) mice and protects against diabetes
Clinical & Experimental Immunology·1998· 83 citedOpen Access
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Frequent Co-authors

Chantal Mathieu(23), Roger Bouillon(13), Mark Waer(13), Jozef Laureys(10), Brigitte Decallonne(7), Lut Overbergh(6), Jos Depovere(6), Annapaula Giulietti(5), Kristina Casteels(5), Conny Gysemans(5), Annemieke Verstuyf(4), Omer Rutgeerts(4), R. Bouillon(4), Evelyne van Etten(4), Lut Overbergh(3), Lutgart Overbergh(3), L. M. KUSCHNAROFF(3), Jozef Goebels(3), Hubertine Heremans(3), Jos Laureys(2)