Simbarashe Zvada

Stellenbosch University — South Africa

Medicine · Health Sciences

10h-index805citations19works0.02yr avg
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Research Topics

HIV/AIDS drug development and treatment(7), HIV Research and Treatment(6), Tuberculosis Research and Epidemiology(4), Pharmacogenetics and Drug Metabolism(4), Antibiotics Pharmacokinetics and Efficacy(4)

Publications19 total

Pharmacokinetic-pharmacodynamic modelling of atazanavir in hair among adolescents on antiretroviral treatment in Zimbabwe
BMC Pharmacology and Toxicology·2021Open Access
FDA approval summary: Dalteparin for the treatment of symptomatic venous thromboembolism in pediatric patients
Pediatric Blood & Cancer·2020· 7 cited
A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: a study of HIV-infected Zimbabwean adolescents
BMC Pharmacology and Toxicology·2020· 4 citedOpen Access
A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: A study of HIV-infected Zimbabwean adolescents.
Research Square (Research Square)·2020· 1 citedOpen Access
A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: A study of HIV-infected Zimbabwean adolescents.
2020Open Access
A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir: A study of HIV-infected Zimbabwean adolescents.
2020· 1 citedOpen Access
Does Hepatic Impairment Affect the Exposure of Monoclonal Antibodies?
Clinical Pharmacology & Therapeutics·2020· 16 cited
A Population Pharmacokinetic Analysis Shows that Arylacetamide Deacetylase (AADAC) Gene Polymorphism and HIV Infection Affect the Exposure of Rifapentine
Antimicrobial Agents and Chemotherapy·2019· 27 citedOpen Access
CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe
BMC Pharmacology and Toxicology·2015· 77 citedOpen Access
High-Dose Rifapentine with Moxifloxacin for Pulmonary Tuberculosis
New England Journal of Medicine·2014· 436 citedOpen Access
Population pharmacokinetics of rifampicin, pyrazinamide and isoniazid in children with tuberculosis: in silico evaluation of currently recommended doses
Journal of Antimicrobial Chemotherapy·2014· 60 citedOpen Access
Optimization of 1st-line antituberculosis dosing regimens using a population pharmacokinetic approach: food effects, drug combinations and pharmacological effects
Open University of Cape Town (University of Cape Town)·2014Open Access
Moxifloxacin Population Pharmacokinetics and Model-Based Comparison of Efficacy between Moxifloxacin and Ofloxacin in African Patients
Antimicrobial Agents and Chemotherapy·2013· 44 citedOpen Access
Pharmacometrics: Opportunity for Reducing Disease Burden in the Developing World: The Case of Africa
CPT Pharmacometrics & Systems Pharmacology·2013· 26 citedOpen Access
PREDICTING POTENTIAL CYP450 ENZYME INHIBITION BASED DRUG-DRUG INTERACTION DURING DRUGS PRESCRIPTION USING A COMPUTER AID
University of Zimbabwe Institutional Repository (University of Zimbabwe)·2013Open Access
Moxifloxacin Population Pharmacokinetics in Patients with Pulmonary Tuberculosis and the Effect of Intermittent High-Dose Rifapentine
Antimicrobial Agents and Chemotherapy·2012· 33 citedOpen Access
Effects of Four Different Meal Types on the Population Pharmacokinetics of Single-Dose Rifapentine in Healthy Male Volunteers
Antimicrobial Agents and Chemotherapy·2010· 43 citedOpen Access
In Vitro and in Silico Identification and Characterization of Thiabendazole as a Mechanism-Based Inhibitor of CYP1A2 and Simulation of Possible Pharmacokinetic Drug-Drug Interactions
Drug Metabolism and Disposition·2009· 28 cited
An Experimental Pharmacokinetic Computer Program to Predict Potential Drug-Drug Interactions
The Open Drug Metabolism Journal·2009· 2 citedOpen Access

Frequent Co-authors

Helen McIlleron(7), Bernard Ngara(6), Paolo Denti(5), Tariro Dianah Chawana(5), Charles Fungai Brian Nhachi(5), Simbarashe Rusakaniko(5), Amina Jindani(4), Thomas S. Harrison(4), Mark Hatherill(4), Ulrika S. H. Simonsson(4), Babill Stray‐Pedersen(4), Salome Charalambous(3), Stanley Mungofa(3), Collen Masimirembwa(3), Lubbe Wiesner(3), Hennie Geldenhuys(2), Andrew Nunn(1), Patrick Phillips(1), Gavin Churchyard(1), Nasir A. Shah(1)