Mitsuhiko Okigaki

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index5.1kcitations126works0.02yr avg
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Research Topics

Angiogenesis and VEGF in Cancer(20), Atherosclerosis and Cardiovascular Diseases(14), Nitric Oxide and Endothelin Effects(11), Cell Adhesion Molecules Research(9), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(9)

Publications126 total

Mucinous tubular and spindle cell carcinoma with a high nuclear grade and micropapillary pattern: A case report
Molecular and Clinical Oncology·2017· 13 citedOpen Access
A case of CD10-negative angioimmunoblastic T cell lymphoma with leukemic change and increased plasma cells mimicking plasma cell leukemia: A case report
Oncology Letters·2015· 10 citedOpen Access
The focal adhesion kinase Pyk2 links Ca2+ signalling to Src family kinase activation and protein tyrosine phosphorylation in thrombin-stimulated platelets
Biochemical Journal·2015· 34 cited
A nuclear factor-κB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates GVHD in allogeneic bone marrow transplantation
Immunobiology·2015· 8 cited
Activation of phosphatidylinositol 3-kinase β by the platelet collagen receptors integrin α2β1 and GPVI: The role of Pyk2 and c-Cbl
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2015· 28 cited
Abstract 69: Possible Involvement Of Proline-rich Tyrosine Kinase 2 (pyk2) In The Pathogenesis Of Kawasaki Disease
Circulation·2015
Enhancement of Ischemia-Induced Angiogenesis by eNOS Overexpression
2015· 100 cited
Involvement of mannose-binding lectin in the pathogenesis of Kawasaki disease-like murine vasculitis
Clinical Immunology·2014· 15 cited
Distinct Role of Pyk2 in Mediating Thromboxane Generation Downstream of Both G12/13 and Integrin αIIbβ3 in Platelets
Journal of Biological Chemistry·2013· 21 citedOpen Access
A Novel Nuclear Factor κB Inhibitor, Dehydroxymethylepoxyquinomicin, Ameliorates Puromycin Aminonucleoside-Induced Nephrosis in Mice
American Journal of Nephrology·2013· 27 cited
The proline‐rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside‐in signaling
Journal of Thrombosis and Haemostasis·2012· 37 citedOpen Access
Impaired thrombin-induced platelet activation and thrombus formation in mice lacking the Ca2+-dependent tyrosine kinase Pyk2
Blood·2012· 48 citedOpen Access
Abstract 17029: Periaortic Adipose Tissue-Specific Activation of Renin Angiotensin System Along with the Adipocytes Differentiation Contributes to Atherosclerosis in Apoe-/- Mice
Circulation·2012
Switching to an L/N-Type Calcium Channel Blocker Shows Renoprotective Effects in Patients with Chronic Kidney Disease: The Kyoto Cilnidipine Study
Journal of International Medical Research·2012· 18 citedOpen Access
Macrophages play a unique role in the plaque calcification by enhancing the osteogenic signals exerted by vascular smooth muscle cells
Biochemical and Biophysical Research Communications·2012· 75 cited
Abstract 340: Phenotypic Conversion of Perivascular Adipose Tissue in Uninephrectomized Apoe-Deficient Mice: Possible Role in the Early Stage of Atherosclerosis in Chronic Kidney Disease
Arteriosclerosis Thrombosis and Vascular Biology·2012
Abstract 339: Impaired Periaortic Adipocyte Differentiation in Angiotensin AT1 Receptor-Deficient Mice: Possible Role in Proinflammatory Phenotypic Modulation of Perivascular Adipose Tissue
Arteriosclerosis Thrombosis and Vascular Biology·2012
Abstract 528: Bone Marrow Angiotensin AT2 Receptor Deficiency Aggravates Atherosclerosis by Eliminating Macrophage Liver X Receptor-Mediated Antiatherogenic Actions
Arteriosclerosis Thrombosis and Vascular Biology·2012
Contents Vol. 48, 2012
Ophthalmic Research·2012Open Access
Neuroprotective Effects of Granulocyte Colony-Stimulating Factor on Ischemia-Reperfusion Injury of the Retina
Ophthalmic Research·2012· 22 citedOpen Access
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Frequent Co-authors

Hiroaki Matsubara(33), Satoaki Matoba(12), Koji Ikeda(11), Tomosaburo Takahashi(11), Toshiji Iwasaka(10), Yasukiyo Mori(9), Hiroyuki Yamada(8), Tetsuya Tatsumi(8), Yasushi Adachi(8), Akihiro Matsui(7), Marco Falasca(6), Gianni Francesco Guidetti(6), Mauro Torti(6), Masahiro Koide(5), Norifumi Urao(5), Shinsaku Matsunaga(5), Kento Tateishi(5), Tomomi Ueyama(5), Tetsuro Kusaba(5), Katsuya Amano(5)