Anu Autio

Orion Corporation (Finland) — Finland

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index881citations36works1.32yr avg
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Research Topics

Microbial metabolism and enzyme function(11), Medical Imaging Techniques and Applications(8), Immunotherapy and Immune Responses(7), Phagocytosis and Immune Regulation(7), Radiopharmaceutical Chemistry and Applications(5)

Publications36 total

Stabilizing Long CARs for Optimal Anti-Tumor Responses in Hematological Malignancies
2025Open Access
Establishing a GMP-compliant manufacturing process and phase-appropriate analytics for early development of a FiCAR T-cell product with a novel CAR spacer
Scientific Reports·2025· 4 citedOpen Access
Abstract 47: Stabilization of long CAR T cells is crucial for in vivo antitumor efficacy
Cancer Research·2024
1044 High dose of rhIL-10 enhances CD8 T cell and NK cell mediated tumor cell killing in vitro
Regular and Young Investigator Award Abstracts·2023· 1 citedOpen Access
Exhausted T cells hijacking the cancer-immunity cycle: Assets and liabilities
Frontiers in Immunology·2023· 33 citedOpen Access
SIRPα - CD47 axis regulates dendritic cell-T cell interactions and TCR activation during T cell priming in spleen
PLoS ONE·2022· 6 citedOpen Access
Role of Brown and Beige Adipose Tissues in Seasonal Adaptation in the Raccoon Dog (Nyctereutes procyonoides)
International Journal of Molecular Sciences·2021· 7 citedOpen Access
Targeted inhibition of CD47-SIRPα requires Fc-FcγR interactions to maximize activity in T-cell lymphomas
Blood·2019· 65 citedOpen Access
Increased lymphocyte activation and atherosclerosis in CD47-deficient mice
Scientific Reports·2019· 32 citedOpen Access
68Ga-DOTA chelate, a novel imaging agent for assessment of myocardial perfusion and infarction detection in a rodent model
Journal of Nuclear Cardiology·2019· 17 citedOpen Access
Impaired CD47–SIRPα Interactions in Antigen‐Priming Results in Defects in Proliferation In Vivo
The FASEB Journal·2019
Antibody blockade of CD47‐SIRPα axis is protective in the murine model of Experimental Autoimmune Encephalomyelitis
The FASEB Journal·2019· 1 cited
<sup>68</sup>Ga-DOTA-E[c(RGDfK)]<sub>2</sub> PET Imaging of SHARPIN-Regulated Integrin Activity in Mice
Journal of Nuclear Medicine·2019· 14 citedOpen Access
Targeted Inhibition of CD47-Sirp Alpha Requires Fc-Fc Gamma Receptor Interactions to Maximize Phagocytosis in T-Cell Lymphomas
Blood·2018· 1 citedOpen Access
A Comparative<sup>68</sup>Ga-Citrate and<sup>68</sup>Ga-Chloride PET/CT Imaging of<i>Staphylococcus aureus</i>Osteomyelitis in the Rat Tibia
Contrast Media & Molecular Imaging·2018· 12 citedOpen Access
Comparison of <sup>68</sup>Ga-DOTA-Siglec-9 and <sup>18</sup>F-Fluorodeoxyribose-Siglec-9: Inflammation Imaging and Radiation Dosimetry
Contrast Media & Molecular Imaging·2017· 8 citedOpen Access
Defects in CD4+ T cell LFA-1 integrin-dependent adhesion and proliferation protect <i>Cd47</i>−/− mice from EAE
Journal of Leukocyte Biology·2016· 15 citedOpen Access
Erratum to: Absorption, distribution and excretion of intravenously injected 68Ge/68Ga generator eluate in healthy rats, and estimation of human radiation dosimetry
EJNMMI Research·2016Open Access
USF1 deficiency activates brown adipose tissue and improves cardiometabolic health
Science Translational Medicine·2016· 74 cited
68Ga-DOTA-Siglec-9 – a new imaging tool to detect synovitis
Arthritis Research & Therapy·2015· 39 citedOpen Access
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Frequent Co-authors

Anne Roivainen(23), Sirpa Jalkanen(11), Heidi Liljenbäck(10), Tiina Saanijoki(7), Gail Newton(7), Francis W. Luscinskas(7), Tuula Tolvanen(6), Riikka Viitanen(6), Meeri Käkelä(6), Pauliina Luoto(6), Tiina Ujula(5), Anil K. Thotakura(5), Vesa Oikonen(5), Satu Salomäki(4), Juhani Knuuti(4), Helena E. Virtanen(4), Mika Teräs(4), Hannu Sipilä(4), Pertti Lehikoinen(3), Petteri Lankinen(3)