John H. Krystal

Boston University — United States

Medicine · Health Sciences

157h-index87.5kcitations1.0kworks6.12yr avg
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Research Topics

Treatment of Major Depression(199), Functional Brain Connectivity Studies(163), Neuroscience and Neuropharmacology Research(153), Tryptophan and brain disorders(148), Neurotransmitter Receptor Influence on Behavior(134)

Publications1.0k total

In memoriam: Professor Dan J. Stein (1962-2025) — a global pioneer with an African heart
The International Journal of Neuropsychopharmacology·2025Open Access
A translational neuroscience & computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial
Journal of Psychiatric Research·2025
Addressing New Challenges to Scientific Integrity Including Paper Mills, Citation Cartels, Coercive Citation Practices, Fake Reviewers, and Artificial Intelligence–Generated Papers
Biological Psychiatry·2025
Efficacy and safety of iclepertin for cognitive impairment associated with schizophrenia (CONNEX programme): results from three phase 3 randomised controlled trials
The Lancet Psychiatry·2025· 2 cited
Mapping DNA Methylation Signatures to Identify Epigenetic Variation Across Subcortical Regions of the Human Posttraumatic Stress Disorder Brain
Biological Psychiatry·2025
Addressing mental health challenges in clinical practice: a qualitative study to investigate perspectives of international mental health experts
European Archives of Psychiatry and Clinical Neuroscience·2025Open Access
M13. DISENTANGLING THE PREFRONTAL CORTEX MULTI-OMIC PROFILE OF OPIOID MISUSE AND POST-TRAUMATIC STRESS DISORDER COMORBIDITY
European Neuropsychopharmacology·2025
A Framework for Advancing Mechanistic Neurobehavioral Biomarkers in Psychiatry
Biological Psychiatry·2025· 1 citedOpen Access
TRANSCRIPTOMIC AND CHROMATIN DYNAMICS OF THE HUMAN PTSD BRAIN AT SINGLE CELL RESOLUTION
European Neuropsychopharmacology·2025
Beta bursts mediate amygdala gating of hippocampal emotional encoding
2025Open Access
A remote care navigation solution associated with improved utilization and outcomes of mental healthcare: A nationwide cohort study in the USA
PLoS ONE·2025Open Access
Developmental timing of index trauma exposure and accelerated epigenetic aging in United States military veterans
Psychoneuroendocrinology·2025
Ketamine for Depression, but at What Cost? A Review of Ketamine’s Neurotoxic Effects From Preclinical and Human Studies
American Journal of Psychiatry·2025· 4 cited
Opposing Modulation of EEG Aperiodic Component by Ketamine and Thiopental: Implications for the Noninvasive Assessment of Cortical E/I Balance in Humans
2025Open Access
Building a Coalition for Change: The Yale Department of Psychiatry Accountability, Respect, Community & Humanity Task Force
Psychiatric Services·2025
Antidepressant efficacy of ketamine plus naltrexone for major depression comorbid with alcohol use disorder: a randomized controlled trial
The International Journal of Neuropsychopharmacology·2025· 2 citedOpen Access
The impact of chronic pain on brain gene expression
Pain·2025· 3 citedOpen Access
Biological Psychiatry: A Brief Note of Thanks
Biological Psychiatry·2025
Interactions of alcohol and the benzodiazepine inverse agonist in healthy male volunteers
Journal of Psychopharmacology·2025
Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD
Nature·2025· 23 citedOpen Access
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Frequent Co-authors

Dennis S. Charney(13), Gerard Sanacora(12), Ralitza Gueorguieva(8), Ronald S. Duman(6), Graeme F. Mason(6), Steven M. Southwick(5), Douglas L. Rothman(5), Robert Berman(4), Marc Laruelle(4), Anissa Abi‐Dargham(4), Alan Anticevic(4), John D. Murray(4), J. Douglas Bremner(4), Amit Anand(3), Roberto Gil(3), Ronald M. Baldwin(3), John Seibyl(3), Deepak Cyril D’Souza(3), Michael W. Cole(3), Joan Kaufman(3)