Mikko Hiltunen

University of Eastern Finland — Finland

Medicine · Health Sciences

46h-index13.8kcitations155works6.02yr avg
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Research Topics

Alzheimer's disease research and treatments(50), Neuroinflammation and Neurodegeneration Mechanisms(19), Cerebrospinal fluid and hydrocephalus(16), Genetic Associations and Epidemiology(15), Amyotrophic Lateral Sclerosis Research(14)

Publications138 total

Frontotemporal dementia patient-derived iPSC neurons show cell pathological hallmarks and evidence for synaptic dysfunction and DNA damage
Molecular Psychiatry·2025· 1 citedOpen Access
Intracerebroventricular phospho-tau immunotherapy alleviates cortical phospho-tau burden and motor phenotype in a neuron-specific P301S tauopathy mouse
Experimental Neurology·2025Open Access
Mitigation of Acute Seizures and Neuropathology after Traumatic Brain Injury by Structure-Based Discovery-Identified Drugs
Journal of Neurotrauma·2025· 1 cited
A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s disease
Nature Medicine·2025· 62 citedOpen Access
Narcolepsy as a potential risk factor for Schizophrenia
Translational Psychiatry·2025· 3 citedOpen Access
Early amyloid spine response and impaired synaptic transmission of pyramidal neurons in human biopsies with Alzheimer’s Disease-related pathology
2025· 2 citedOpen Access
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer’s disease
Molecular Therapy·2024· 3 citedOpen Access
Extremely rare CNVs contributing to Alzheimer disease risk: a case-control association analysis of exome sequencing data from 22,319 individuals
2024Open Access
Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes
Fluids and Barriers of the CNS·2024· 4 citedOpen Access
Genetic Susceptibility to Acute Viral Bronchiolitis
The Journal of Infectious Diseases·2024· 5 citedOpen Access
Protective variant in PLCγ2 mitigates Alzheimer’s disease-associated pathologies via enhancing beneficial microglia functions
2024Open Access
Risk Variants Associated With Normal Pressure Hydrocephalus
Neurology·2024· 21 citedOpen Access
Deep learning assisted quantitative analysis of Aβ and microglia in patients with idiopathic normal pressure hydrocephalus in relation to cognitive outcome
Journal of Neuropathology & Experimental Neurology·2024· 1 citedOpen Access
Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes
2024Open Access
Fibroblasts carrying intermediate <i>C9orf72</i> hexanucleotide repeat expansions from iNPH patients show impaired energy metabolism but no cell pathologies
2024Open Access
Monoallelic <i>TYROBP</i> deletion is a novel risk factor for Alzheimer’s disease
2024· 4 citedOpen Access
X-Chromosome-wide association study for Alzheimer’s disease
2024Open Access
Frontotemporal dementia patient-derived iPSC neurons show cell pathological hallmarks and evidence for synaptic dysfunction and DNA damage
2024Open Access
High-Resolution Genotyping of Formalin-Fixed Tissue Accurately Estimates Polygenic Risk Scores in Human Diseases
Laboratory Investigation·2024· 5 citedOpen Access
Inferring compound heterozygosity from large-scale exome sequencing data
Nature Genetics·2023· 30 citedOpen Access
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Frequent Co-authors

Hilkka Soininen(21), Seppo Ylä‐Herttuala(15), Seppo Helisalmi(12), Anne M. Koivisto(9), Ville Leinonen(9), Mikko P. Turunen(7), Juha Rutanen(6), Irina Alafuzoff(6), Ossi Nerg(5), Sanna‐Kaisa Herukka(5), Tuomas T. Rissanen(5), Annakaisa Haapasalo(5), Anne M. Remes(5), Petra Mäkinen(5), Tuomas Rauramaa(5), Jean‐Charles Lambert(4), Philippe Amouyel(4), Anna‐Mari Turunen(4), Henrik Zetterberg(4), Okko T. Pyykkö(4)