John Holyoake

Ontario Institute for Cancer Research — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index868citations20works0.02yr avg
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Research Topics

Lipid Membrane Structure and Behavior(6), Ion channel regulation and function(6), Protein Structure and Dynamics(3), Nicotinic Acetylcholine Receptors Study(3), Neuroscience and Neuropharmacology Research(2)

Publications20 total

Construction and validation of a homology model of the human voltage-gated proton channel hHV1
The Journal of General Physiology·2013· 77 citedOpen Access
Detergent-mediated protein aggregation
Chemistry and Physics of Lipids·2013· 13 citedOpen Access
Accessibility of the S4 Arginines in the Human Voltage Gated Proton Channel, hHV1
Biophysical Journal·2013· 1 citedOpen Access
Structure of saposin A lipoprotein discs
Proceedings of the National Academy of Sciences·2012· 96 citedOpen Access
Does Aspartate112 Mutation Convert the Human Voltage Gated Proton Channel into a Hydroxide Channel?
Biophysical Journal·2012Open Access
A Homology Modeling-Simulation Protocol for Construction and Assessment of Hv1 Models
Biophysical Journal·2012· 1 citedOpen Access
The structure of SapA lipoprotein discs
Acta Crystallographica Section A Foundations of Crystallography·2011Open Access
A general and Efficient All-Atom Simulation Method to Determine the Equilibrium Orientation of Transmembrane Proteins in Membranes
Biophysical Journal·2011Open Access
Molecular Basis for the Solvation and Reconstructive Denaturation of Proteins by Detergents
Biophysical Journal·2010Open Access
DNA and lipid bilayers: self-assembly and insertion
Journal of The Royal Society Interface·2008· 70 citedOpen Access
Molecular Dynamics Studies of Membrane Proteins: Outer Membrane Proteins and Transporters
2007
Conformational Change in an MFS Protein: MD Simulations of LacY
Structure·2007· 74 citedOpen Access
Coarse-grained molecular dynamics simulations of membrane proteins and peptides
Journal of Structural Biology·2006· 320 cited
Modeling, Docking, and Simulation of the Major Facilitator Superfamily
Biophysical Journal·2006· 33 citedOpen Access
KcsA closed and open: modelling and simulation studies
European Biophysics Journal·2003· 31 cited
Ion channel gating: insights via molecular simulations
FEBS Letters·2003· 134 citedOpen Access
Initial Teacher Training: the French view
Journal of Education for Teaching International Research and Pedagogy·1993· 16 cited
A critical study of the tragedies of Robert Garnier (1545-90)
1987· 2 cited
Is Ignorance Desirable? A New Approach to an Old Problem in Montaigne's Essais
Nottingham French Studies·1986
Montaigne: 'Essais'
The Modern Language Review·1986

Frequent Co-authors

Régis Pomès(9), Mark S.P. Sansom(7), Gilbert G. Privé(4), Kethika Kulleperuma(4), Susan M. Smith(4), Deri Morgan(4), Boris Musset(4), Vladimir V. Cherny(4), Thomas E. DeCoursey(4), Peter J. Bond(3), Syma Khalid(3), Nilmadhab Chakrabarti(3), Cármen Domene(2), K. Popovic(2), Anthony Ivetac(1), Oliver Beckstein(1), Philip C. Biggin(1), Joanne N. Bright(1), Alessandro Grottesi(1), Robert W. Hawtin(1)